Now showing items 11-20 of 88
Oxidation of substituted 4-fluorobenzaldehydes: Application to the no-carrier-added syntheses of 4-[18F]fluoroguaiacol and 4-[18F]fluorocatechol
(Elsevier, 1991)
The synthesis of 4-[18F]fluoroguaiacol (4-[18F]fluoro-2-methoxyphenol) has been achieved in no-carrier-added form starting from 2-methoxy-4-nitrobenzaldehyde, using nucleophilic aromatic substitution by [18F]fluoride ...
Synthesis of a [11C]Methoxy derivative of [alpha]-Dihydrotetrabenazine: a radioligand for studying the vesicular monoamine transporter
(Elsevier, 1993-12)
The synthesis of [11C]TBZOMe, a [11C]methoxy derivative at the 2-hydroxy position of [alpha]-dihydrotetrabenazine, was carried out by an O-[11C]methylation reaction. The product [11C]TBZOMe (100-200 mCi) was obtained in ...
Radioiodination via isotope exchange in pivalic acid
(Elsevier, 1986)
A variety of benzoic and aryl aliphatic mono and polyiodinated acids and esters (sterol, triglyceride) were radioiodinated in 55-99% radiochemical yield by isotope exchange with Na 125I in a melt of pivalic acid. In general, ...
CT evaluation of mediastinal masses
(Elsevier, 1987)
CT is an important modality for imaging mediastinal masses, and certain CT attenuation features (fat, calcium, or water attenuation, contrast enhancement) are well known to suggest specific diagnoses. In a series of 132 ...
Synthesis of [18F]flunarizine
(Elsevier, 1991)
Flunarizine, a calcium channel antagonist of the piperazine class, has been labeled with the positron-emitter 18F. 4-[18F]Fluoro-4'-fluorobenzhydryl chloride was prepared in three steps from no-carrier-added [18F]fluoride ...
Monte Carlo evaluation of object shape effects in iodine-131 SPET tumor activity quantification
(Springer-Verlag, 2001-07)
In our clinical iodine-131 single-photon emission tomography (SPET) quantification for radioimmunotherapy, calibration and partial volume correction are based on measurements with phantoms containing spheres to simulate ...
Selective localization of radioiodinated alkylphosphocholine derivatives in tumors
(Elsevier, 1992-10)
We have designed and synthesized two radioiodinated analogs of hexadecylphosphocholine in order to evaluate their tumor imaging potential. 12-(m[125I]iodophenyl)dodecyl phosphocholine (NM-324) and hexadecyl-2-[N,N-dimeth ...
Scintigraphy of incidentally discovered bilateral adrenal masses
(Springer-Verlag, 1995-04)
The purpose of this study was to determine the patterns of iodine-131 6β-iodomethylnorcholesterol (NP-59) imaging and the correlation with computed tomography (CT)-guided adrenal biopsy and follow-up in patients with ...
CT evaluation of the equivocal pulmonary nodule
(Elsevier, 1987)
In the setting of a questionable pulmonary nodule demonstrated by conventional radiographs, the place of CT in the diagnostic algorithm is not well established. We reviewed our experience in 50 consecutive patients referred ...