Now showing items 21-30 of 88
Toxicity from treatment of neuroblastoma with 131 I-meta-iodobenzylguanidine
(Springer-Verlag, 1988-09)
Toxic effects from 131 I-meta-iodobenzylguanidine ( 131 I-MIBG) treatments of neuroblastoma in six patients were recorded. The toxicity was largely confined to the hematologic system where circulating leukocytes and platelets ...
Metabolic fate of the heart agent [18F]6-fluorometaraminol
(Elsevier, 1989)
Studies were performed to determine whether [18F]6-fluorometaraminol (18F-FMR), a new neuronal heart radiopharmaceutical, is metabolized in vivo and if the metabolites are taken up in heart. Rat, dog, baboon and guinea pig ...
Evaluation of ( E )-2′-deoxy-2′-(fluoromethylene)cytidine on the 9L rat brain tumor model using MRI
(John Wiley & Sons, Ltd., 2003-04)
( E )-2′-deoxy-2′-(fluoromethylene)cytidine (FMdC), was evaluated as a potential treatment for malignant gliomas using the rat 9L brain tumor model. FMdC was shown to be an effective inhibitor of cell proliferation in ...
Routine production of 2-deoxy-2-[18F]fluoro--glucose by direct nucleophilic exchange on a quaternary 4-aminopyridinium resin
(Elsevier, 1990)
Resin-supported [18F]fluoride ion has been prepared and applied to a rapid, convenient synthesis of [18F]FDG. "No-carrier-added" [18F]fluoride ion is collected on a quaternary 4-(N, N-dialkylamino)-pyridinium functionalized ...
Iodine-125 and fluorine-18 labeled aryl-1,4-dialkylpiperazines: Potential radiopharmaceuticals for in vivo study of the dopamine uptake system
(Elsevier, 1992-05)
A series of fluorine-18 and iodine-125 labeled aryl-1,4-dialkylpiperazine analogs, derivatives of GBR 12935, were synthesized as radiotracers for positron emission tomography or single photon emission computerized tomography ...
Potential of a Compton camera for high performance scintimammography
(IOP Publishing Ltd, 2004-02-21)
In this paper, we present a novel approach to scintimammography that is based on the Compton camera principle. We analyse the performance of our scheme using Monte Carlo simulations. In particular, we evaluate the detection ...
[18F]fluorination/decarbonylation: New route to aryl [18F]fluorides
(Elsevier, 1991)
A new route to aryl [18F]fluorides without electron withdrawing ring substituents has been developed. [18F]Fluorobenzaldehydes, prepared from no-carrier-added (NCA) [18F]fluoride using nucleophilic aromatic substitution ...
Use of DES-treated rats as an animal model for assessment of pituitary adenoma imaging agents
(Elsevier, 1986)
Prolactin (PRL) secreting pituitary adenomas are the most common type of pituitary tumors. An imaging agent which specifically localized in prolactinomas would be of considerable clinical value for both initial detection ...
Application of ART to time-coded emission tomography
(IOP Publishing Ltd, 1979-09-01)
Using the Algebraic Reconstruction Techniques (ART) a method is introduced for division of the correlation coefficients into subsets allowing the three-dimensional reconstruction to be accomplished on a minicomputer. Results ...
Computer-aided diagnosis in mammography: classification of mass and normal tissue by texture analysis
(IOP Publishing Ltd, 1994-12-01)
Computer-aided diagnosis schemes are being developed to assist radiologists in mammographic interpretation. In this study, the authors investigated whether texture features could be used to distinguish between mass and ...