Now showing items 1-10 of 88
Synthesis and regional mouse brain distribution of [11C]Nisoxetine, a norepinephrine uptake inhibitor
(Elsevier, 1989)
Nisoxetine, a selective and high affinity (IC50 = 1 nM) inhibitor of NE reuptake, has been radiolabeled in high specific activity (> 600 Ci/mmol) by the alkylation of the nor-methyl precursor with [11C]CH3I. Synthetic ...
CT and ultrasound in abscess detection at specific anatomic sites: A study of 198 patients
(Elsevier, 1987)
Records of 902 patients with possible abdominal abscess were reviewed and of these 198 had abscesses on at least one occasion imaged either with ultrasound (US) or computed tomography (CT). There were 235 episodes of either ...
In vivo 31 P MRS evaluation of ganciclovir toxicity in C6 gliomas stably expressing the herpes simplex thymidine kinase gene
(John Wiley & Sons, Ltd., 1996-12)
Phosphorus MRS was evaluated as a monitor of tumour therapeutic response to the herpes simplex virus thymidine kinase suicide gene therapy paradigm. In vivo 31 P spectra were obtained from subcutaneous rat C6 gliomas ...
Evaluation of ( - )[18F]fluoroethoxybenzovesamicol as a new PET tracer of cholinergic neurons of the heart
(Elsevier, 1994-02)
18F-labeled ( - )fluoroethoxybenzovesamicol [( - )FEOBV] is a novel PET tracer which binds to the vesicular acetylcholine transporter of cholinergic neurons. To evaluate the in vivo binding specificity and kinetic properties ...
Characterization of [11C]tetrabenazine as an in vivo radioligand for the vesicular monoamine transporter
(Elsevier, 1994-02)
[11C]Tetrabenazine ([11C]TBZ) is a new in vivo radioligand for positron emission tomographic (PET) imaging of vesicular monoamine transporters. The in vivo distribution, metabolism and pharmacological specificity of [11C]TBZ ...
Pragmatic fully 3D image reconstruction for the MiCES mouse imaging PET scanner
(IOP Publishing Ltd, 2004-10-07)
We present a pragmatic approach to image reconstruction for data from the micro crystal elements system (MiCES) fully 3D mouse imaging positron emission tomography (PET) scanner under construction at the University of ...
Effects of magnification and zooming on depth perception in digital stereomammography: an observer performance study
(IOP Publishing Ltd, 2003-11-21)
We are evaluating the application of stereoscopic imaging to digital mammography. In the current study, we investigated the effects of magnification and zooming on depth perception. A modular phantom was designed which ...
Feasibility of sharpening limited-angle tomography by including an orthogonal set of projections
(Elsevier, 1982-02-15)
In single photon emission nuclear medicine, computed tomography systems that employ only a limited angular range of projection data suffer from blurring in the depth (or z) direction. With simulated data, we show that ...