Now showing items 11-20 of 83
Massive locally extensive prostate cancer
(Elsevier, 1994-02)
A massive, locally extensive adenocarcinoma of the prostate (2,246 ccm) presenting as constipation and a palpable abdominal mass, was treated with androgen deprivation resulting in a 94 percent reduction in tumor size, and ...
Decreased galectin-3 expression in prostate cancer
(John Wiley & Sons, Inc., 2000-07-01)
BACKGROUND Galectin-3 is a carbohydrate-binding protein whose level of expression has been shown to be correlated with metastatic potential in a number of different tumor types. The purpose of this investigation was to ...
Truncated E-cadherin potentiates cell death in prostate epithelial cells
(Wiley Subscription Services, Inc., A Wiley Company, 2005-05-15)
BACKGROUND E-cadherin, a fundamental component of the adherens junction, is known to mediate aggregation-dependent cell survival. We have previously identified a novel, calpain-dependent proteolytic cleavage of E-cadherin ...
The discovery and application of gene fusions in prostate cancer
(Blackwell Publishing Ltd, 2008-08)
Analysis of the gene coding for the BRCA2-Interacting protein PALB2 in hereditary prostate cancer
(Wiley Subscription Services, Inc., A Wiley Company, 2008-05-01)
BACKGROUND The genetic basis of susceptibility to prostate cancer (PRCA) remains elusive. Mutations in BRCA2 have been associated with increased prostate cancer risk and account for around 2% of young onset (<56 years) ...
The Benign Prostatic Hyperplasia Registry and Patient Survey: study design, methods and patient baseline characteristics
(Blackwell Publishing Ltd, 2007-10)
To describe the design and baseline cohort characteristics of the Benign Prostatic Hyperplasia (BPH) Registry and Patient Survey, an ongoing, prospective, observational, disease registry documenting management practices ...
Effect of alpha-adrenergic blockade and anticholinergic agents on the decentralized primate bladder
(Wiley Subscription Services, Inc., A Wiley Company, 1985)
The effect of anticholinergic and alpha-adrenergic blocking agents on the primate bladder decentralized at the sacral level was studied. Both agents diminish the intravesical pressure response to filling and slightly ...
Dickkopf-1 expression increases early in prostate cancer development and decreases during progression from primary tumor to metastasis
(Wiley Subscription Services, Inc., A Wiley Company, 2008-09-15)
BACKGROUND Prostate cancer (PCa) frequently metastasizes to the bone and induces osteoblastic lesions. We previously demonstrated through over-expression of the Wnt inhibitor dickkopf-1 (DKK-1) that Wnts contribute to the ...
Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men Anna M. Ray and Kimberly A. Zuhlke contributed equally to this work.
(Wiley Subscription Services, Inc., A Wiley Company, 2009-06-15)
BACKGROUND Previous studies have found associations between mitochondrial DNA (mtDNA) mutations and several cancer types. Recently, we found that mutations in the mtDNA gene cytochrome c oxidase subunit 1 ( COI ) were ...
Ureterocele associated with a single collecting system of the involved kidney
(Elsevier, 1994-06)
Objective. This is a study concerning ureteroceles associated with a single collecting system of the involved kidney.Methods. Over an eight-year period 9 children (5 boys, 4 girls) had a ureterocele subtending a single ...