Now showing items 31-40 of 83
Sequence variation in Α-methylacyl-CoA racemase and risk of early-onset and familial prostate cancer
(Wiley Subscription Services, Inc., A Wiley Company, 2007-10-01)
BACKGROUND Expression of the Α-methylacyl-CoA racemase ( AMACR ) gene has been established as a sensitive and specific biomarker for the diagnosis of prostate cancer. An initial study has also suggested that the risk of ...
Mechanisms of urethral continence and their clinical application
(Springer-Verlag, 1984-12)
Controversy about the basic nature of urethral function does not preclude accurate clinical assessment of disorders of function. While the precise method of treatment of urethral continence dysfunction varies from institution ...
Immunologic Detection of the Cellular Receptor for Urokinase Plasminogen Activator
(Elsevier, 1994-04)
The cellular receptor for urokinase plasminogen activator (uPA-R) is a monomeric phosphatidylinositol-linked glycoprotein (gp40-65) that may contribute to the invasive capacity of tumor and inflammatory cells by focusing ...
Standardization of radical cystectomy: Time to count and be counted
(Blackwell Science Ltd, 2004-09)
Osteoblasts produce soluble factors that induce a gene expression pattern in non-metastatic prostate cancer cells, similar to that found in bone metastatic prostate cancer cells
(Wiley Subscription Services, Inc., A Wiley Company, 2002-04-01)
BACKGROUND Progressive prostate cancer typically metastasizes to bone where prostate cancer cells gain an osteoblast-like phenotype and induce osteoblastic metastases through unknown mechanisms. To investigate the biology ...
EGFR ligand switch in late stage prostate cancer contributes to changes in cell signaling and bone remodeling
(Wiley Subscription Services, Inc., A Wiley Company, 2009-04-01)
BACKGROUND Bone metastasis occurs frequently in advanced prostate cancer (PCa) patients; however, it is not known why this happens. The epidermal growth factor receptor (EGFR) ligand EGF is available to early stage PCa; ...
Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro
(John Wiley & Sons, Inc., 2001-05-15)
BACKGROUND Prostate cancer frequently metastasizes to bone. However, unlike many other tumors that produce osteolytic lesions, prostate cancer produces osteoblastic lesions through unknown mechanisms. In the current study, ...
Long-term results and complications using augmentation cystoplasty in reconstructive urology
(Wiley Subscription Services, Inc., A Wiley Company, 1995)
One hundred and twenty-two augmentation cystoplasties performed over an 8-year period were reviewed. Mean age at surgery was 37 years (range 2–82 years). There were 82 female patients. The primary urodynamic diagnosis was ...
Expression and activation of Α v Β 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells
(Wiley Subscription Services, Inc., A Wiley Company, 2007-01-01)
BACKGROUND Stromal cell-derived factor-1 (SDF-1 or CXCL12) and CXCR4 are key elements in the metastasis of prostate cancer cells to bone—but the mechanisms as to how it localizes to the marrow remains unclear. METHODS ...