Search Constraints
Number of results to display per page
View results as:
Search Results
-
- Creator:
- Bustamante, Angela C., Opron, Kristopher, Ehlenbach, William J., Crane, Paul K., Keene, Dirk, Standiford, Theodore J., and Singer, Benjamin H.
- Description:
- This study was conducted to detect and analyze modules, or clusters of genes, associated with sepsis, using RNAseq data obtained from 12 participants who died of sepsis and 12 participants who died of non-infectious critical illness while hospitalized. This deposit contains the input data and parameters needed to reproduce the weighted gene co-expression network analysis (WGCNA) and gene enrichment analysis performed on this data. This analysis requires the R packages "WGCNA" version 1.68 and "DESeq2" version 1.22.2 available for download from bioconductor ( http://bioconductor.org). The external bioinformatics tool DAVID version 6.8 ( https://david.ncifcrf.gov/) was used as an additional gene enrichment analysis. Please see the supplemental methods document within this deposit and published research letter for more detailed information.
- Keyword:
- Sepsis, RNAseq, Transcriptomics, Human, and Brain
- Citation to related publication:
- Bustamante, A.C., Opron, K., Ehlenbach, W.J., Larson, E.B., Crane, P.K., Keene, C.D., Standiford, T.J., Singer, B.H., 2020. Transcriptomic Profiles of Sepsis in the Human Brain. Am J Respir Crit Care Med. https://doi.org/10.1164/rccm.201909-1713LE
- Discipline:
- Science
-
- Creator:
- McCuen, Brett A.
- Description:
- These data are TLA events identified in MACCS magnetometer data throughout 2015. These events are short-timescale (< 60 s), large -amplitude (> 6 nT/s) magnetic disturbances measured at Earth's surface that are analyzed for space weather research purposes. and The events were identified in a year's worth of magnetic field data using an algorithm developed in the MATLAB platform. The algorithm dBdt_main.m can be run using the associated scripts (clean_maccs.m, simple_dbdt.m, extremes1.m, newdbdt.m) to return the events in the 2015_AllEvents.csv file. The substorm onset delays of each event are determined with the onset_delays.m script and the substorm event list 20191127-15-56-substorms.csv (both included).
- Keyword:
- space weather impacts, geomagnetically induced currents, GIC, transient induced currents, transient large amplitude, dB/dt search algorithm, and TLA
- Citation to related publication:
- Engebretson, M. J., Pilipenko, V. A., Ahmed, L. Y., Posch, J. L., Steinmetz, E. S., Moldwin, M. B., … Vorobev, A. V. (2019). Nighttime Magnetic Perturbation Events Observed in Arctic Canada: 1. Survey and Statistical Analysis. Journal of Geophysical Research: Space Physics, 124(9), 7442–7458. https://doi.org/10.1029/2019JA026794
- Discipline:
- Science
-
Transmission of Oral microbiome and Sequencing
User Collection- Creator:
- Lee, Kyu Han
- Description:
- De-identified participant data from household transmission study of influenza in Nicaragua Oligotype count table and taxonomic classifications
- Keyword:
- Influenza and Microbiome
- Discipline:
- Health Sciences
2Works -
- Creator:
- Lee, Kyu Han, Foxman, Betsy, and Gordon, Aubree
- Description:
- Data include variables used to run mixed effects models examining the association between the nose/throat microbiome and influenza virus infection. Certain individual participant data have been excluded due to identifiability concerns. Data also include the oligotype count table and taxonomic classifications. and Curation Notes: Readme updated Nov. 29, 2018 with context for oligotype and taxonomy files, and citation to associated article.
- Keyword:
- Influenza and Microbiome
- Citation to related publication:
- Lee KH, Gordon A, Shedden K, Kuan G, Ng S, Balmaseda A, Foxman B. The respiratory microbiome and susceptibility to influenza virus infection. PloS One. 2019;14:e0207898. https://doi.org/10.1371/journal.pone.0207898
- Discipline:
- Health Sciences
-
- Creator:
- Lee, Kyu Han
- Description:
- Data include variables used to run accelerated failure time models examining the association between the nose/throat microbiome and 1) symptom duration, 2) shedding duration, and 3) time to infection. Certain individual participant data have been excluded due to identifiability concerns. Data also include the oligotype count table and taxonomic classifications.
- Keyword:
- Influenza and Microbiome
- Citation to related publication:
- Lee KH, Gordon A, Shedden K, Kuan G, Ng S, Balmaseda A, Foxman B. The respiratory microbiome and susceptibility to influenza virus infection. PloS One. 2019;14:e0207898. https://doi.org/10.1371/journal.pone.0207898
- Discipline:
- Health Sciences
-
- Creator:
- Goodrich, Jaclyn M., Tang, Lu, Rodríguez-Carmona, Yanelli, Meijer, J L., Perng, Wei, Watkins, Deborah J., Meeker, John D. , Mercado-García, Adriana, Cantoral, Alejandra, Song, Peter X. , Téllez-Rojo, Martha M. , and Peterson, Karen E.
- Description:
- Phthalates are chemicals found in many products that humans are exposed to. Prenatal exposure to phthalates has been associated with adverse outcomes that are detected in childhood, adolescence, and even adulthood. In this study, we sought to identify subtle biological changes in the metabolome of children that were exposed to phthalates during gestation. We hypothesized that prenatal phthalate exposures would alter metabolic pathways related to adiposity and cardiometabolic health. The article is under review (citation to be added when paper is published). The data included here encompass all exposure, demographic, and untargeted metabolomics data needed for the analysis described in the manuscript.
- Keyword:
- Phthalates , Prenatal, and Metabolomics
- Citation to related publication:
- Goodrich J.M., Tang L.,Rodríguez-Carmona Y., Meijer J.L, Perng W., Watkins D.J., Meeker J.D., Mercado-García A., Cantoral A., Song P.X., Téllez-Rojo M.M., Peterson K.E. Trimester-specific phthalate exposures in pregnancy are associated with circulating metabolites in children. PLoS One. (Under revision – forthcoming.)
- Discipline:
- Other and Health Sciences
-
- Creator:
- Towne, Aaron, Yeh, Chi-An., Patel, Het, and Taira, Kunihiko
- Description:
- This dataset contains data from a three-dimensional large eddy simulation of Mach 0.3 flow over a NACA 0012 airfoil at Reynolds number 23,000, which features a transitional boundary layer, separation over a recirculation bubble, and a turbulent wake. The dataset contains 16,000 time-resolved snapshots of the mid-span and spanwise-averaged velocity fields. All data are stored within hdf5 files, and a Matlab script showing how the data can be read and manipulated is provided. Please see the ‘airfoilLES_README.pdf’ file for more information. We recommend using the ‘airfoilLES_example.zip’ file as an entry point to the dataset. and The dataset is part of “A database for reduced-complexity modeling of fluid flows” (see references below) and is intended to aid in the conception, training, demonstration, evaluation, and comparison of reduced-complexity models for fluid mechanics. The paper introduces the flow setup and computational methods, describes the available data, and provides an example of how these data can be used for reduced-complexity modeling. Users of these data should cite the papers listed below.
- Citation to related publication:
- Towne, A., Dawson, S., Brès, G. A., Lozano-Durán, A., Saxton-Fox, T., Parthasarthy, A., Biler, H., Jones, A. R., Yeh, C.-A., Patel, H., Taira, K. (2022). A database for reduced-complexity modeling of fluid flows. AIAA Journal 61(7): 2867-2892. and Yeh, C.-A. and Taira, K. (2019) Resolvent-analysis-based design of airfoil separation control. Journal of Fluid Mechanics, 867:572–610.
- Discipline:
- Science and Engineering
-
- Creator:
- Towne, Aaron S. and Lozano-Durán, Adrián
- Description:
- This dataset contains data from two direct numerical simulations of a turbulent zero-pressure-gradient flat-plate boundary layer spanning friction Reynolds numbers from 292 to 728 (BL1) and 488 to 1024 (BL2). The dataset contains time-resolved snapshots of the three-dimensional velocity field for both cases: roughly 10,000 snapshots spanning 20 eddy-turnover times for BL1 and 7,500 snapshots spanning 7 eddy-turnover times for BL2 . Also included for both cases are pre-processed correlations at several wall-normal distances, mean and root-mean-squared velocity and vorticity profiles, several boundary-layer metrics, and time-resolved velocity data in the streamwise-wall-normal plane. All data are stored within hdf5 files, and a Matlab script showing how the data can be read and manipulated is provided. Please see the ‘BLdns_README.pdf’ file for more information. We recommend using the ‘BLdns_example.zip’ file as an entry point to the dataset. and The dataset is part of “A database for reduced-complexity modeling of fluid flows” (see references below) and is intended to aid in the conception, training, demonstration, evaluation, and comparison of reduced-complexity models for fluid mechanics. The paper introduces the flow setup and computational methods, describes the available data, and provides an example of how these data can be used for reduced-complexity modeling. Users of these data should cite the paper listed below.
- Keyword:
- fluid mechanics, boundary layer, and turbulence
- Citation to related publication:
- Towne, A., Dawson, S., Brès, G. A., Lozano-Durán, A., Saxton-Fox, T., Parthasarthy, A., Biler, H., Jones, A. R., Yeh, C.-A., Patel, H., Taira, K. (2022). A database for reduced-complexity modeling of fluid flows. AIAA Journal 61(7): 2867-2892.
- Discipline:
- Engineering and Science
-
- Creator:
- Towne, Aaron, Saxton-Fox, Theresa, and Parthasarthy, Aadhy
- Description:
- This dataset contains experimental measurements of a zero-pressure-gradient flat-plate boundary layer at five different Reynolds numbers collected using particle image velocimetry. For each Reynolds number, the dataset contains approximately 6000 snapshots of planar velocity fields as well as raw particle image pairs. All data are stored within hdf5 files, and a Matlab script showing how the data can be read and manipulated is provided. Please see the ‘BLexp_README.pdf’ file for more information. We recommend using the ‘BLexp_example.zip’ file as an entry point to the dataset. and The dataset is part of “A database for reduced-complexity modeling of fluid flows” (see references below) and is intended to aid in the conception, training, demonstration, evaluation, and comparison of reduced-complexity models for fluid mechanics. The paper introduces the flow setup and computational methods, describes the available data, and provides an example of how these data can be used for reduced-complexity modeling. Users of these data should cite the papers listed below.
- Keyword:
- fluid mechanics
- Citation to related publication:
- Towne, A., Dawson, S., Brès, G. A., Lozano-Durán, A., Saxton-Fox, T., Parthasarthy, A., Biler, H., Jones, A. R., Yeh, C.-A., Patel, H., Taira, K. (2022). A database for reduced-complexity modeling of fluid flows. AIAA Journal 61(7): 2867-2892.
- Discipline:
- Engineering and Science
-
- Creator:
- Towne, Aaron S. and Brès, Guillaume
- Description:
- This dataset contains data from a large eddy simulation of a turbulent jet at Mach number 0.9. The dataset contains 10000 time-resolved snapshots of three-dimensional velocity, density, and pressure fields spanning 2000 acoustic time units and also includes pre-processed azimuthal Fourier modes for each snapshot and the mean flow. All data are stored within hdf5 files, and a Matlab script showing how the data can be read and manipulated is provided. Please see the ‘jet_README.pdf’ file for more information. We recommend using the ‘jet_example.zip’ file as an entry point to the dataset. and The dataset is part of “A database for reduced-complexity modeling of fluid flows” (see references below) and is intended to aid in the conception, training, demonstration, evaluation, and comparison of reduced-complexity models for fluid mechanics. The paper introduces the flow setup and computational methods, describes the available data, and provides two examples of how these data can be used for reduced-complexity modeling. Users of these data should cite the two papers listed below.
- Keyword:
- fluid mechanics, jets, and turbulence
- Citation to related publication:
- Towne, A., Dawson, S., Brès, G. A., Lozano-Durán, A., Saxton-Fox, T., Parthasarthy, A., Biler, H., Jones, A. R., Yeh, C.-A., Patel, H., Taira, K. (2022). A database for reduced-complexity modeling of fluid flows. AIAA Journal 61(7): 2867-2892. and Brès, G. A., Jordan, P., Jaunet, V., Le Rallic, M., Cavalieri, A. V. G., Towne, A., Lele, S. K., Colonius, T., Schmidt, O. T. (2018) Importance of the nozzle-exit boundary-layer state in subsonic turbulent jets. J. Fluid Mech., 851:83–124.
- Discipline:
- Engineering and Science