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- Creator:
- Abraczinskas, Carol and Capobianco, Alessio
- Description:
- These files (.tiff format) provide high-resolution images of a fossil specimen complementing the formal description of the osteoglossid fish †Macroprosopon hiltoni from the Eocene (Ypresian) of Morocco.
- Keyword:
- Paleontology, Fossil, Osteoglossidae, FSAC, Faculty of Sciences Aïn Chock, Casablanca, Morocco, and Eocene
- Discipline:
- Science
-
Zagorë
User Collection
- Creator:
- Galaty, Michael
- Description:
- The following works contain the databases, field notebooks, unit and profile drawings, photographs, photo descriptions, radiocarbon dates, and geophysical survey data related to the Zagorë settlement excavation.
- Keyword:
- archaeology
- Discipline:
- Science and Humanities
4Works -
- Creator:
- Holmes, Iris A, Monagan Jr., Ivan V, Westphal, Michael F, and Davis Rabosky, Alison R
- Description:
- We generated these data from desert night lizards, Xantusia vigilis, from populations in central California. We performed phylogeographic analyses based on these data.
- Keyword:
- ddRADseq, phylogeography, Xantusia vigilis, lizard, and genome-scale sequencing
- Discipline:
- Science
-
- Creator:
- Steiner, A.L. and Kawecki, S.
- Description:
- Kansas City, MO emissions can affect a severe weather system by altering the number of CCN, which drives changes in the hydrometeor development. The hydrometeor changes affect cold pool strength, size, and propagation which ultimately determine the strength of the squall line that crosses Kansas City, MO.
- Keyword:
- Great Plains, aerosols, mesoscale convective systems, and weather
- Discipline:
- Science
-
- Creator:
- Steiner, Allison and Kawecki, Stacey
- Description:
- WRF-Chem model
- Keyword:
- aerosols and weather
- Discipline:
- Science
-
- Creator:
- Cody H. Pham, Jason M. Tallant, J. Jordan Price, and David N. Karowe
- Description:
- Anthropogenic climate change will dramatically alter species distributions. The rate and magnitude of range shifts, however, will differ among taxa, resulting in altered patterns of co-occurrence and interspecific interactions. We examined potential climate-mediated breeding range shifts among North American wood-warblers (Parulidae), a speciose avian family likely to be especially impacted by such changes. We used publicly available species distribution model (SDM) range outputs to compare current ranges and patterns of sympatry among warbler species to future ranges and sympatry under 1.5 °C, 2.0 °C, and 3.0 °C of average global warming. We used these outputs to calculate average breeding range area, range overlap among species, number of sympatric species, and distances of breeding range shifts. We additionally calculated the number gained and lost sympatric interactions under each warming scenario.
- Keyword:
- wood-warbler, University of Michigan Biological Station (UMBS), Research Experience for Undergraduates (REU), climate change, interspecific, range shift, species distribution models, sympatric, and student-friendly
- Discipline:
- Science
-
- Creator:
- Johnson, JE and Molnar, PH
- Description:
- This IF compilation was assembled from the existing literature to understand if preservation biases affected the record of iron formations.
- Keyword:
- Archean ocean chemistry, temporal record of iron formations, and early Earth iron cycle
- Citation to related publication:
- Johnson, J. E., & Molnar, P. H. ( 2019). Widespread and persistent deposition of iron formations for two billion years. Geophysical Research Letters, 46, 3327– 3339. https://doi.org/10.1029/2019GL081970
- Discipline:
- Science
-
- Creator:
- Revzen, Shai
- Description:
- This repository contains both the data and python3 code that reads this data and reproduces the relevant figures. The code depends on NumPy >1.17 and matplotlib >3.1 and was tested on python 3.8
- Keyword:
- locomotion, slipping, low Reynolds number, walking, and slithering
- Discipline:
- Science and Engineering
-
- Creator:
- Sun, Hu, Ren, Jiaen, Chen, Yang, Zou, Shasha, Chang, Yurui, Wang, Zihan, and Coster, Anthea
- Description:
- Our research focuses on providing a fully-imputed map of the worldwide total electron content with high resolution and spatial-temporal smoothness. We fill in the missing values of the original Madrigal TEC maps via estimating the latent feature of each latitude and local time along the 2-D grid and give initial guess of the missing regions based on pre-computed spherical harmonics map. The resulting TEC map has high imputation accuracy and the ease of reproducing. All data are in HDF5 format and are easy to read using the h5py package in Python. The TEC map is grouped in folders based on years and each file contains a single-day data of 5-min cadence. Each individual TEC map is of size 181*361. and WARNING: 2023-12-01 the data file for 2019-Jan-03 has badly fitted values. Please avoid using it. All other days' files are ready to use.
- Keyword:
- Total Electron Content, Matrix Completion, VISTA, Spherical Harmonics, and Spatial-Temporal Smoothing
- Citation to related publication:
- Sun, H., Hua, Z., Ren, J., Zou, S., Sun, Y., & Chen, Y. (2022). Matrix completion methods for the total electron content video reconstruction. The Annals of Applied Statistics, 16(3), 1333-1358., Sun, H., Chen, Y., Zou, S., Ren, J., Chang, Y., Wang, Z., & Coster, A. (2023). Complete Global Total Electron Content Map Dataset based on a Video Imputation Algorithm VISTA. Scientific Data, in press., and Zou, S., Ren, J., Wang, Z., Sun, H., & Chen, Y. (2021). Impact of storm-enhanced density (SED) on ion upflow fluxes during geomagnetic storm. Frontiers in Astronomy and Space Sciences, 8, 746429.
- Discipline:
- Science and Engineering
-
- Creator:
- Sun, Hu, Ren, Jiaen, Chen, Yang, and Zou, Shasha
- Description:
- Our research focuses on providing a fully-imputed map of the worldwide total electron content with high resolution and spatial-temporal smoothness. We fill in the missing values of the original Madrigal TEC maps via estimating the latent feature of each latitude and local time along the 2-D grid and give initial guess of the missing regions based on pre-computed spherical harmonics map. The resulting TEC map has high imputation accuracy and the ease of reproducing. and All data are in HDF5 format and are easy to read using the h5py package in Python. The TEC map is grouped in folders based on years and each file contains a single-day data of 5-min cadence. Each individual TEC map is of size 181*361.
- Keyword:
- Total Electron Content, Matrix Completion, VISTA, Spherical Harmonics, and Spatial-Temporal Smoothing
- Citation to related publication:
- Sun, H., Hua, Z., Ren, J., Zou, S., Sun, Y., & Chen, Y. (2020). Matrix Completion Methods for the Total Electron Content Video Reconstruction. arXiv preprint arXiv:2012.01618. and Zou, S., Ren, J., Wang, Z., Sun, H., & Chen, Y. (2021). Impact of Storm-Enhanced Density (SED) on Ion Upflow Fluxes During Geomagnetic Storm. Frontiers in Astronomy and Space Sciences, 162.
- Discipline:
- Science
-
- Creator:
- Walsh, Lisa L
- Description:
- Stable isotope values of carbon (δ13C) and nitrogen (δ15N) from Virginia opossum (Didelphis virginiana) guard hairs were analyzed to evaluate the ecology and winter adaptations in opossums by Dr. Lisa L. Walsh as part of her Ph.D. thesis in the Ecology and Evolutionary Biology Department. The collection of stable isotope data took place from 2017 to 2019. Guard hair was processed at the University of Michigan and analyzed by the University of New Mexico Center for Stable Isotopes (UNM-CSI, USA). Captive and wild opossums were evaluated for evidence of biannual or incomplete biannual molting, a mammalian adaptation to harsh winters. Results suggest opossums do not exhibit either winter molting strategy and that guard hairs capture the opossum’s lifetime diet (Walsh and Tucker 2021). The stable isotope values were used to test the hypothesis that a Type A generalist’s niche is positively correlated with habitat heterogeneity and to evaluate which climate variables best explained isotope values. There was a positive correlation between isotopic niche size and habitat-diversity indexes (Walsh and Tucker 2020). The δ13C values from opossums in the Midwest and Northeast to test whether opossums rely on anthropogenic trash to survive extreme winters. There was no significant relationship between δ13C and winter variables, but there was a significant increase in variance of Midwest opossums’ δ13C after the 1970 corn agricultural boom (Walsh and Tucker 2023).
- Keyword:
- stable isotope, Virginia opossum, mesopredator, ecology, and mammal
- Citation to related publication:
- Walsh, L.L. and P.K. Tucker. 2020. Habitat heterogeneity is correlated with isotopic niche breadth across the range of a mammalian generalist mesopredator. Ecosphere, 11(12): e03314. https://doi.org/10.1002/ecs2.3314, Walsh, L.L. and P.K. Tucker. 2021. Stable isotope values suggest opossums (Didelphis virginiana) at their northern edge do not seasonally molt. Northeastern Naturalist, 28(1): 1-8. https://doi.org/10.1656/045.028.0101, and Walsh, L.L., and P.K. Tucker. 2023. Evaluating anthropogenic influence on a mesopredator: Opossum (Didelphis virginiana) isotope values influenced by corn agriculture more than urbanization. Canadian Journal of Zoology, 101: https://doi.org/10.1139/cjz-2021-0172.
- Discipline:
- Science
-
Video data of predation and parasitism by arthropods on small vertebrates in lowland Peruvian Amazon
- Creator:
- Grundler, Michael C, Grundler, Maggie G, and Herrera, V.
- Description:
- Nighttime and diurnal surveys in the lowland Peruvian Amazon of Los Amigos Biological Station were conducted in order to describe herpetological diversity at this site. As a result of these surveys, the predation event between a Pamphobeteus sp. and Marmosops sp. and the myiasis of Ranitomeye uakarii were observed. The video footage was recorded in order to document these interesting interactions between arthropod predators and parasites and vertebrate prey and hosts, and are included for publication in the short communication "Ecological interactions between arthropods and small vertebrates in a lowland Amazon rainforest" in the journal Amphibian and Reptile Conservation.
- Keyword:
- Amazonia, predator-prey, spiders, opposums, frogs, and myiasis
- Citation to related publication:
- von May R, Biggi E, Cárdenas H, Diaz MI, Alarcón C, Herrera V, Santa-Cruz R, Tomasinelli F, Westeen E, Sánchez-Paredes CM, Larson JG, Title PO, Grundler MR, Grundler MC, Davis Rabosky AR, Rabosky DL (2019) Ecological interactions between arthropods and small vertebrates in a lowland Amazon rainforest. Amphibian and Reptile Conservation 13(1): 65–77. http://amphibian-reptile-conservation.org/pdfs/Volume/Vol_13_no_1/ARC_13_1_[General_Section]_65-77_e169_high_res.pdf
- Discipline:
- Science
-
- Creator:
- Bougher, S. W. and Parkinson, C. D.
- Description:
- Understanding the state and composition of an exoplanetary atmosphere depends upon several parameters such as heating, cooling, mixing and reactions between constituent chemical species. Only a few types of atmospheric species can be detected remotely spectroscopically and only if their abundance is large enough to be detectable. In this initial study, we model the atmosphere of a Venus-like planet orbiting the M-type star GJ 436 to determine the global neutral temperature structure, winds, and energy balance as the radial distance of the planet from the star decreases.
- Keyword:
- Venus-like exoplanet, upper atmospheres , and heat balances
- Citation to related publication:
- C. D. Parkinson, S. W. Bougher, F. P. Mills, R. Hu, G. Gronoff, J. Li, A. Brecht, D. Adams, and Y. L. Yung. Venus as an Exoplanet: I. An Initial Exploration of the 3-D Energy Balance for a CO2 Exoplanetary Atmosphere Around an M-Dwarf Star, J. Geophysical Research, X, (2022). doi:....
- Discipline:
- Science
-
- Creator:
- Ma, Sicong and Keane, Sarah
- Description:
- These files are the original data for the publication of 'Use of steric blocking antisense oligonucleotides for the targeted inhibition of junction containing precursor microRNAs': https://doi.org/10.1101/2024.04.08.588531. This dataset contains the original gel image files for the processing assay results, luciferase data readout, and the original data file for qPCR results reported in the publication.
- Citation to related publication:
- Use of steric blocking antisense oligonucleotides for the targeted inhibition of junction containing precursor microRNAs Sicong Ma, Samantha A. Howden, Sarah C. Keane bioRxiv 2024.04.08.588531; doi: https://doi.org/10.1101/2024.04.08.588531
- Discipline:
- Science
-
University of Michigan Museum of Zoology
User Collection
- Creator:
- University of Michigan Museum of Zoology
- Description:
- The University of Michigan Museum of Zoology (UMMZ) is the center for the study of animal diversity on campus, focusing on the evolutionary origins of the planet’s animal species, the genetic information they contain and the communities and ecosystems they help form. Now an integral part of the Department of Ecology and Evolutionary Biology (EEB), the UMMZ houses world-class collections, containing more than 15 million specimens, span almost 200 years of regional and global biodiversity studies and that support a multi-faceted Departmental research and teaching program.
- Discipline:
- Science
4Sub-collections0Works -
- Creator:
- Engel, Daniel D. , Evans, Mary Anne, Low, Bobbi S., and Schaeffer, Jeff
- Description:
- This dataset was compiled as an attempt to understand how natural resource managers and research ecologists in the Great Lakes region integrate the ecosystem services (ES) paradigm into their work. The following text is the adapted abstract from a thesis associated with this data. Ecosystem services, or the benefits people obtain from ecosystems, have gained much momentum in natural resource management in recent decades as a relatively comprehensive approach to provide quantitative tools for improving decision-making and policy design. However, to date we know little about whether and how natural resource practitioners, from natural resource managers to research ecologists (hereafter managers and ecologists respectively), have adopted the ES paradigm into their respective work. Here, we addressed this knowledge gap by asking managers and ecologists about whether and how they have adopted the ES paradigm into their respective work. First, we surveyed federal, state, provincial and tribal managers in the Great Lakes region about their perception and use of ES as well as the relevance of specific services to their work. Although results indicate that fewer than 31% of the managers said they currently consider economic values of ES, 79% of managers said they would use economic information on ES if they had access to it. Additionally, managers reported that ES-related information was generally inadequate for their resource management needs. We also assessed managers by dividing them into identifiable groups (e.g. managers working in different types of government agencies or administrative levels) to evaluate differential ES integration. Overall, results suggest a desire among managers to transition from considering ES concepts in their management practices to quantifying economic metrics, indicating a need for practical and accessible valuation techniques. Due to a sample of opportunity at the USGS Great Lakes Science Center (GLSC), we also evaluated GLSC research ecologists’ integration of the ES paradigm because they play an important role by contributing requisite ecological knowledge for ES models. Managers and ecologists almost unanimously agreed that it was appropriate to consider ES in resource management and also showed convergence on the high priority ES. However, ecologists appeared to overestimate the adequacy of ES-related information they provide as managers reported the information was inadequate for their needs. This divergence may reflect an underrepresentation of ecological economists in this system who can aid in translating ecological models into estimates of human well-being. As a note, the dataset for the research ecologists has had some data removed as it could be considered personally identifiable information due to the small sample size in that population. The surveys associated with both datasets have also been included in PDF format. Curation Notes: Three files were added to the data set on Dec 21, 2017. Two csv files: "Ecosystem services and Research Ecologists - Data Index.csv" and "Ecosystem services and Research Managers - Data Index.csv" and one text file: "Ecosystem Services Adoption Readme.txt". The file names of the original four files were altered to replace an ampersand with the word "and".
- Keyword:
- Research Ecologist, Decision-Making, Ecosystem Services, Natural Resource Management, Paradigm Adoption, and Ecological Economics
- Discipline:
- Science and Social Sciences
-
- Creator:
- Song, Siliang and Zhang, Jianzhi
- Description:
- Fitness landscapes map genotypes to their corresponding fitness under given environments and allow explaining and predicting evolutionary trajectories. Of particular interest is the landscape ruggedness or the unevenness of the landscape, because it impacts many aspects of evolution such as the likelihood that a population is trapped in a local fitness peak. Although the ruggedness has been inferred from a number of empirically mapped fitness landscapes, it is unclear to what extent this inference is affected by fitness estimation error, which is inevitable in the experimental determination of fitness landscapes. Here we address this question by simulating fitness landscapes under various theoretical models, with or without fitness estimation error. We find that all eight examined measures of landscape ruggedness are overestimated due to imprecise fitness quantification, but different measures are affected to different degrees. We devise a method to use replicate fitness measures to correct this bias and show that our method performs well under realistic conditions. We conclude that previously reported fitness landscape ruggedness is likely upward biased owing to the negligence of fitness estimation error and advise that future fitness landscape mapping should include at least three biological replicates to permit an unbiased inference of the ruggedness.
- Keyword:
- adaptation, estimation error, evolution, NK model, Rough Mount Fuji model, and polynomial model
- Discipline:
- Science
-
- Creator:
- Al Shidi, Qusai. and Pulkkinen, Tuija.
- Description:
- This is part of the simulation set of geomagnetic storms from 2010 to 2019. The Space Weather Modeling Framework (SWMF) with the configuration of SWPC v2 was used. The output files can be read by the visualization scripts included in the SWMF or the SpacePy Python package.
- Keyword:
- space weather, space physics, geomagnetic storms, and magnetosphere
- Discipline:
- Science
-
- Creator:
- Towne, Aaron S. and Brès, Guillaume
- Description:
- This dataset contains data from a large eddy simulation of a turbulent jet at Mach number 0.9. The dataset contains 10000 time-resolved snapshots of three-dimensional velocity, density, and pressure fields spanning 2000 acoustic time units and also includes pre-processed azimuthal Fourier modes for each snapshot and the mean flow. All data are stored within hdf5 files, and a Matlab script showing how the data can be read and manipulated is provided. Please see the ‘jet_README.pdf’ file for more information. We recommend using the ‘jet_example.zip’ file as an entry point to the dataset. and The dataset is part of “A database for reduced-complexity modeling of fluid flows” (see references below) and is intended to aid in the conception, training, demonstration, evaluation, and comparison of reduced-complexity models for fluid mechanics. The paper introduces the flow setup and computational methods, describes the available data, and provides two examples of how these data can be used for reduced-complexity modeling. Users of these data should cite the two papers listed below.
- Keyword:
- fluid mechanics, jets, and turbulence
- Citation to related publication:
- Towne, A., Dawson, S., Brès, G. A., Lozano-Durán, A., Saxton-Fox, T., Parthasarthy, A., Biler, H., Jones, A. R., Yeh, C.-A., Patel, H., Taira, K. (2022). A database for reduced-complexity modeling of fluid flows. AIAA Journal 61(7): 2867-2892. and Brès, G. A., Jordan, P., Jaunet, V., Le Rallic, M., Cavalieri, A. V. G., Towne, A., Lele, S. K., Colonius, T., Schmidt, O. T. (2018) Importance of the nozzle-exit boundary-layer state in subsonic turbulent jets. J. Fluid Mech., 851:83–124.
- Discipline:
- Engineering and Science
-
- Creator:
- Towne, Aaron, Saxton-Fox, Theresa, and Parthasarthy, Aadhy
- Description:
- This dataset contains experimental measurements of a zero-pressure-gradient flat-plate boundary layer at five different Reynolds numbers collected using particle image velocimetry. For each Reynolds number, the dataset contains approximately 6000 snapshots of planar velocity fields as well as raw particle image pairs. All data are stored within hdf5 files, and a Matlab script showing how the data can be read and manipulated is provided. Please see the ‘BLexp_README.pdf’ file for more information. We recommend using the ‘BLexp_example.zip’ file as an entry point to the dataset. and The dataset is part of “A database for reduced-complexity modeling of fluid flows” (see references below) and is intended to aid in the conception, training, demonstration, evaluation, and comparison of reduced-complexity models for fluid mechanics. The paper introduces the flow setup and computational methods, describes the available data, and provides an example of how these data can be used for reduced-complexity modeling. Users of these data should cite the papers listed below.
- Keyword:
- fluid mechanics
- Citation to related publication:
- Towne, A., Dawson, S., Brès, G. A., Lozano-Durán, A., Saxton-Fox, T., Parthasarthy, A., Biler, H., Jones, A. R., Yeh, C.-A., Patel, H., Taira, K. (2022). A database for reduced-complexity modeling of fluid flows. AIAA Journal 61(7): 2867-2892.
- Discipline:
- Engineering and Science
-
- Creator:
- Towne, Aaron S. and Lozano-Durán, Adrián
- Description:
- This dataset contains data from two direct numerical simulations of a turbulent zero-pressure-gradient flat-plate boundary layer spanning friction Reynolds numbers from 292 to 728 (BL1) and 488 to 1024 (BL2). The dataset contains time-resolved snapshots of the three-dimensional velocity field for both cases: roughly 10,000 snapshots spanning 20 eddy-turnover times for BL1 and 7,500 snapshots spanning 7 eddy-turnover times for BL2 . Also included for both cases are pre-processed correlations at several wall-normal distances, mean and root-mean-squared velocity and vorticity profiles, several boundary-layer metrics, and time-resolved velocity data in the streamwise-wall-normal plane. All data are stored within hdf5 files, and a Matlab script showing how the data can be read and manipulated is provided. Please see the ‘BLdns_README.pdf’ file for more information. We recommend using the ‘BLdns_example.zip’ file as an entry point to the dataset. and The dataset is part of “A database for reduced-complexity modeling of fluid flows” (see references below) and is intended to aid in the conception, training, demonstration, evaluation, and comparison of reduced-complexity models for fluid mechanics. The paper introduces the flow setup and computational methods, describes the available data, and provides an example of how these data can be used for reduced-complexity modeling. Users of these data should cite the paper listed below.
- Keyword:
- fluid mechanics, boundary layer, and turbulence
- Citation to related publication:
- Towne, A., Dawson, S., Brès, G. A., Lozano-Durán, A., Saxton-Fox, T., Parthasarthy, A., Biler, H., Jones, A. R., Yeh, C.-A., Patel, H., Taira, K. (2022). A database for reduced-complexity modeling of fluid flows. AIAA Journal 61(7): 2867-2892.
- Discipline:
- Engineering and Science
-
- Creator:
- Towne, Aaron, Yeh, Chi-An., Patel, Het, and Taira, Kunihiko
- Description:
- This dataset contains data from a three-dimensional large eddy simulation of Mach 0.3 flow over a NACA 0012 airfoil at Reynolds number 23,000, which features a transitional boundary layer, separation over a recirculation bubble, and a turbulent wake. The dataset contains 16,000 time-resolved snapshots of the mid-span and spanwise-averaged velocity fields. All data are stored within hdf5 files, and a Matlab script showing how the data can be read and manipulated is provided. Please see the ‘airfoilLES_README.pdf’ file for more information. We recommend using the ‘airfoilLES_example.zip’ file as an entry point to the dataset. and The dataset is part of “A database for reduced-complexity modeling of fluid flows” (see references below) and is intended to aid in the conception, training, demonstration, evaluation, and comparison of reduced-complexity models for fluid mechanics. The paper introduces the flow setup and computational methods, describes the available data, and provides an example of how these data can be used for reduced-complexity modeling. Users of these data should cite the papers listed below.
- Citation to related publication:
- Towne, A., Dawson, S., Brès, G. A., Lozano-Durán, A., Saxton-Fox, T., Parthasarthy, A., Biler, H., Jones, A. R., Yeh, C.-A., Patel, H., Taira, K. (2022). A database for reduced-complexity modeling of fluid flows. AIAA Journal 61(7): 2867-2892. and Yeh, C.-A. and Taira, K. (2019) Resolvent-analysis-based design of airfoil separation control. Journal of Fluid Mechanics, 867:572–610.
- Discipline:
- Science and Engineering
-
- Creator:
- McCuen, Brett A.
- Description:
- These data are TLA events identified in MACCS magnetometer data throughout 2015. These events are short-timescale (< 60 s), large -amplitude (> 6 nT/s) magnetic disturbances measured at Earth's surface that are analyzed for space weather research purposes. and The events were identified in a year's worth of magnetic field data using an algorithm developed in the MATLAB platform. The algorithm dBdt_main.m can be run using the associated scripts (clean_maccs.m, simple_dbdt.m, extremes1.m, newdbdt.m) to return the events in the 2015_AllEvents.csv file. The substorm onset delays of each event are determined with the onset_delays.m script and the substorm event list 20191127-15-56-substorms.csv (both included).
- Keyword:
- space weather impacts, geomagnetically induced currents, GIC, transient induced currents, transient large amplitude, dB/dt search algorithm, and TLA
- Citation to related publication:
- Engebretson, M. J., Pilipenko, V. A., Ahmed, L. Y., Posch, J. L., Steinmetz, E. S., Moldwin, M. B., … Vorobev, A. V. (2019). Nighttime Magnetic Perturbation Events Observed in Arctic Canada: 1. Survey and Statistical Analysis. Journal of Geophysical Research: Space Physics, 124(9), 7442–7458. https://doi.org/10.1029/2019JA026794
- Discipline:
- Science
-
- Creator:
- Bustamante, Angela C., Opron, Kristopher, Ehlenbach, William J., Crane, Paul K., Keene, Dirk, Standiford, Theodore J., and Singer, Benjamin H.
- Description:
- This study was conducted to detect and analyze modules, or clusters of genes, associated with sepsis, using RNAseq data obtained from 12 participants who died of sepsis and 12 participants who died of non-infectious critical illness while hospitalized. This deposit contains the input data and parameters needed to reproduce the weighted gene co-expression network analysis (WGCNA) and gene enrichment analysis performed on this data. This analysis requires the R packages "WGCNA" version 1.68 and "DESeq2" version 1.22.2 available for download from bioconductor ( http://bioconductor.org). The external bioinformatics tool DAVID version 6.8 ( https://david.ncifcrf.gov/) was used as an additional gene enrichment analysis. Please see the supplemental methods document within this deposit and published research letter for more detailed information.
- Keyword:
- Sepsis, RNAseq, Transcriptomics, Human, and Brain
- Citation to related publication:
- Bustamante, A.C., Opron, K., Ehlenbach, W.J., Larson, E.B., Crane, P.K., Keene, C.D., Standiford, T.J., Singer, B.H., 2020. Transcriptomic Profiles of Sepsis in the Human Brain. Am J Respir Crit Care Med. https://doi.org/10.1164/rccm.201909-1713LE
- Discipline:
- Science
-
- Creator:
- Butterfield, Zachary, Muccio, Daniel, and Keppel-Aleks, Gretchen
- Description:
- Solar-induced chlorophyll fluorescence (SIF) is an emission of photons during photosynthesis that can be used to make inferences about gross primary productivity (GPP) and carbon uptake of vegetation. With a recent proliferation of available satellite-based observations of SIF, there is much interest in assessing how SIF relates to GPP across multiple temporal and spatial scales. Tower-based observations of SIF at high temporal resolution provide a key link between satellite data and local surface-based observations of ecosystem productivity. We collected tower-based observations of SIF and several vegetation indices using a PhotoSpec spectrometer system deployed on the AmeriFlux tower at UMBS (US-UMB). As the data were collected alongside concurrent eddy flux observations of carbon exchange, they provide a unique opportunity to explore how SIF and other vegetation signals relate to GPP in a temperate deciduous forest and better inform the interpretation of satellite observations.
- Keyword:
- Solar-induced chlorophyll fluorescence, gross primary production, temperate deciduous forest, remote sensing, flux observations, forest productivity
- Citation to related publication:
- Butterfield, Z., Magney, T., Grossmann, K., Bohrer, G., Vogel, C., Barr, S., & Keppel-Aleks, G. (2023). Accounting for Changes in Radiation Improves the Ability of SIF to Track Water Stress-Induced Losses in Summer GPP in a Temperate Deciduous Forest. Journal of Geophysical Research: Biogeosciences, 128, e2022JG007352. https://doi.org/10.1029/2022JG007352
- Discipline:
- Science
-
- Creator:
- Ponder, Brandon M., Ridley, Aaron J., Bougher, Stephen W., Pawlowski, David, and Brecht, Amanda
- Description:
- This research was completed to introduce a state-of-the-art Venus GCM to the modeling community. Validation studies were performed to give credence to the model's results. and This data set is made available under a Creative Commons Public Domain license (CC0 1.0). The python scripts contained were ran on macOS Monterey version 12.7 with Python 3.9. Numpy version: 1.19.4 Pandas version: 1.2.0
- Keyword:
- Venus, GITM, Ionosphere, Thermosphere, Solar minimum, Navier-stokes, Fluid dynamics, Shocks, V-GITM, and VGITM
- Citation to related publication:
- Ponder, Brandon & Ridley, Aaron J. & Bougher, Stephen W. & Pawlowski, D. & Brecht, A. (2023). The Venus Global Ionosphere-Thermosphere Model (V-GITM): A Coupled Thermosphere and Ionosphere Formulation. JGR Planets. In Press.
- Discipline:
- Science
-
- Creator:
- Bueno-Junior, Lezio S., Ruckstuhl, Maxwell S., Lim, Miranda M., and Watson, Brendon O.
- Description:
- Rapid eye movement sleep (REM) is believed to have a binary temporal structure with “phasic” and “tonic" microstates, characterized by motoric activity versus quiescence, respectively. However, we observed in mice that the frequency of theta activity (a marker of rodent REM) fluctuates in a non-binary fashion, with the extremes of that fluctuation correlating with phasic-type and tonic-type facial motricity. Thus, phasic and tonic REM may instead represent ends of a continuum. These cycles of brain physiology and facial movement occurred at 0.01-0.06 Hz, or infraslow frequencies, and affected cross-frequency coupling and neuronal activity in the neocortex, suggesting network functional impact. We then analyzed human data and observed that humans also demonstrate non-binary phasic/tonic microstates, with continuous 0.01-0.04 Hz respiratory rate cycles matching the incidence of eye movements. These fundamental properties of REM can yield new insights into our understanding of sleep health.
- Keyword:
- REM sleep, Infraslow fluctuations, Facial movements, Theta oscillations, and Respiration rate
- Citation to related publication:
- L. S. Bueno-Junior, M. S. Ruckstuhl, M. M. Lim, B. O. Watson, The temporal structure of REM sleep shows minute-scale fluctuations across brain and body in mice and humans. Proc. Natl. Acad. Sci. U. S. A. In press (2023).
- Discipline:
- Science
-
- Creator:
- Hille, Madeline M., Clark, Marin K., Gronewold, Andrew D., West, A. Joshua, Zekkos, Dimitrios , and Chamlagain, Deepak
- Description:
- This dataset supports the findings of Hille et al. (2021, in review) in Geophysical Research Letters. In this article, we present a multivariate analysis of extreme storm events that occur during the Indian summer monsoon over the Himalayan Range in central Nepal. We resolve storm events at sub daily durations by merging NASA’s Global Precipitation Mission (GPM) Integrated Multi-satellitE Retrievals for GPM (IMERG) 30-minute, gridded 0.1x0.1-degree precipitation product with local rain gauges operated by the Nepal Department of Hydrology and Meteorology (DHM) and the International Centre for Integrated Mountain Development (ICIMOD). We quantify spatial variability in extreme rainfall by isolating storms over a specific intensity threshold and pairing a principal components analysis with a K-means clustering approach to group storms of similar characteristics. and We find that frequent and intense storms occur over the forefront of the central Himalayan range and coincide with a locus of monsoon-driven landslide density. This pattern agrees with observations of elevated annual precipitation volumes near the Himalayan physiographic transition from low to high relief (Bookhagen and Burbank, 2010), and is consistent with orographically-influenced rainfall over other mountain ranges (Marra et al., 2021). In addition to presenting novel methodology to quantifying storm variability, our results highlight the strong orographic effect on precipitation intensity and duration, as well as an association of shallow bedrock landsliding frequency with intense precipitation.
- Keyword:
- orographic rainfall, multivariate analysis, extreme rainfall events, and rainfall-triggered landslides
- Citation to related publication:
- Hille et al. (2021, in review). The orographic influence on storm variability, extreme rainfall characteristics and rainfall-triggered landsliding. Geophysical Research Letters. Forthcoming
- Discipline:
- Science
-
- Creator:
- Ozturk, Dogacan Su
- Description:
- The rapid increases in solar wind dynamic pressure, termed sudden impulses (SIs), compress Earth’s dayside magnetosphere and strongly perturb the coupled Magnetosphere-Ionosphere (M-I) system. The compression of the dayside magnetosphere launches magnetohydrodynamic (MHD) waves, which propagate down to the ionosphere, changing the Auroral Field Aligned Currents (FACs), and into nightside magnetosphere. The global response to the compression front sweeping through the coupled system is not yet fully understood due to the sparseness of the measurements, especially those with the necessary time resolution to resolve the propagating disturbances. That’s why a study including modeling is necessary. On 15 August 2015 at 7.44 UT, Advanced Composition Explorer measured a sudden increase in the solar wind dynamic pressure from 1.11 nPa to 2.55 nPa as shown in Figure-1. We use the magnetospheric spacecraft in the equatorial magnetosphere to identify the signatures of magnetosphere response to this SI event and examine the interaction of the propagating disturbances with the M-I system. With the increased time resolution of Active Magnetosphere and Polar Electrodynamics Response Experiment (AMPERE), the FAC pattern and intensity change due to SI can also be studied in more depth. We further use measurements from ground based magnetometer stations to increase our tracking capability for the disturbances in the ionosphere and to improve our understanding of their propagation characteristics. This is the first step in a comprehensive multi-point observation and a global magnetohydrodynamic simulation based investigation of the response of the coupled M-I system to sudden impulses.
- Discipline:
- Science
-
- Creator:
- Malik, Hafiz and Khan, Muhammad Khurran, King Saud University
- Description:
- Details of the microphone used for data collection, acoustic environment in which data was collected, and naming convention used are provided here. 1 - Microphones Used: The microphones used to collect this dataset belong to 7 different trademarks. Table (1) illustrates the number of used Mics of different trademarks and models. Table 1: Trademarks and models of Mics Mic Trademark Mic Model # of Mics Shure SM-58 3 Electro-Voice RE-20 2 Sennheiser MD-421 3 AKG C 451 2 AKG C 3000 B 2 Neumann KM184 2 Coles 4038 2 The t.bone MB88U 6 Total 22 2- Environment Description: A brief description of the 6 environments in which the dataset was collected is presented here: (i) Soundproof room: a small room (nearly 1.5m × 1.5m × 2m), which is closed and completely isolated. With an exception of a small window in the front side of the room which is made of glass, all the walls of the room are made of wood and covered by a layer of sponge from the inner side, and the floor is covered by carpet. (ii) Class room: standard class room (6m × 5m × 3m). (iii) Lab: small lab (4m × 4m × 3m). All the walls are made of glasses and the floor is covered by carpet. The lab contains 9 computers. (iv) Stairs: is in the second floor. The place of recording is 3m × 5m (v) Parking: is the college parking. (vi) Garden: is an open space outside the buildings. 3- Naming Convention: This set of rules were followed as a naming convention to give each file in the dataset a unique name: (i) The file name is 19 characters long, and consists of 5 sections separated by underscores. (ii) The first section is of 3 characters indicates the Microphone trademark. (iii) The second section of 4 characters indicates the microphone model as in table (2). (iv) The third section of 2 characters indicates a specific microphone within a set of microphones of the same trademark and model, since we have more than one microphone of the same trademark and model. (v) The fourth section of 2 characters indicates the environment, where Soundproof room --> 01 Class room --> 02 Lab --> 03 Stairs --> 04 Parking --> 05 Garden --> 06 (vi) The fifth section of 2 characters indicates the language, where Arabic --> 01 English --> 02 Chinese --> 03 Indonesian --> 04 (vii) The sixth section of 2 characters indicates the speaker. Table 2: Microphones Naming Criteria Original Mic Trademark and model --> Naming Convenient Shure SM-58 --> SHU_0058 Electro-Voice RE-20 --> ELE_0020 Sennheiser MD-421 --> SEN_0421 AKG C 451 --> AKG_0451 AKG C 3000 B --> AKG_3000 Neumann KM184 --> NEU_0184 Coles 4038 --> COL_4038 The t.bone MB88U --> TBO_0088 For example: SEN_0421_02_01_02_03 is an English file recorded by speaker number 3 in the soundproof room using microphone number 2 of Sennheiser MD-421
- Keyword:
- audio forensic, multimedia forensics, microphone identification, tamper detection, splicing detection, and codec identification
- Citation to related publication:
- Muhammad Khurram Khan, Mohammed Zakariah, Hafiz Malik & Kim-Kwang Raymond Choo (2018). A novel audio forensic data-set for digital multimedia forensics, Australian Journal of Forensic Sciences, 50:5, 525-542, http://dx.doi.org/10.1080/00450618.2017.1296186
- Discipline:
- Engineering, Government, Politics and Law, and Science
-
- Creator:
- Matt, Cayenne, Gültekin, Kayhan, and Simon, Joseph
- Description:
- The data were used to create number density functions of supermassive black holes (SMBH) for redshifts 0.5 < z < 3.0. The goal of this research is to discern whether galaxy-black hole scaling relations produce black hole masses that are consistent with each other at high redshift. These number density functions were used to compare the high-mass SMBH distributions from each relation. In massive black hole binary based models, the highest-mass SMBHs have a significant influence on the gravitational wave background characteristic strain amplitude. To inform our understanding of the gravitational wave background, that pulsar timing arrays now show evidence for, we need to therefore have a solid foundation on the underlying SMBH population. In our paper we found that using different galaxy properties to inform our estimations of SMBH mass resulted in different distributions, especially at the high-mass end.
- Citation to related publication:
- https://iopscience.iop.org/article/10.1088/0067-0049/219/1/8, https://iopscience.iop.org/article/10.1088/0067-0049/196/1/11, https://iopscience.iop.org/article/10.1088/0004-637X/788/1/28, https://iopscience.iop.org/article/10.3847/1538-4357/ab7e27, and https://ui.adsabs.harvard.edu/abs/2023arXiv230704878M/abstract
- Discipline:
- Science
-
- Creator:
- Wu, Chen/ University of Michigan, Ridley, Aaron/ University of Michigan, and DeJong, Anna/ Howard Community College
- Description:
- 1.5 years of Polar UVI data was used to construct the Feature Tracking empirical model of Auroral Precipitation (FTA). A cumulative energy grid was tracked with the energy flux and the latitude position in each MLT bin for individual images. The auroral characteristics show linear relationships with the AE index depending on the MLT region. Thus, the FTA model was constructed to describe the global energy flux and the averaged energy as a function of the AE index based on the LBHl and LBHs emissions. Compared with two other empirical models, FTA predicted more consistent aurora with the observations on 17 March 2013 at higher activity levels.
- Keyword:
- Aurora, Polar UVI, precipitation model
- Citation to related publication:
- Wu, C., Ridley, A. J., DeJong, A. D., & Paxton, L. J. (2021). FTA: A Feature Tracking Empirical Model Of Auroral Precipitation. Space Weather, 19, e2020SW002629. https://doi.org/10.1029/2020SW002629
- Discipline:
- Science
-
- Creator:
- Xian Li
- Description:
- Low-velocity accretionary wedges and sedimentary layers overlaying continental plates are widely observed in the subduction zones where historical large earthquakes have occurred. It was observed that rupture of the 2011 Mw 9.0 Tohoku-Oki earthquake propagated to the trench with large coseismic slip on the shallow fault, but what caused the huge shallow slip remains a prominent problem., Here we explore how the two low-velocity structures, accretionary wedge and sedimentary layer, affect the coseismic slip and near-fault ground motions during the 2011 Tohoku-Oki earthquake. Constrained by the observed seafloor deformation, we present a 2-D dynamic rupture model of the 2011 Tohoku-Oki earthquake with an accretionary wedge and a sedimentary layer. Compared to a homogeneous model with the same friction and stress parameters on the fault, we find that the co-existence of the accretionary wedge and sedimentary layer significantly enhances the shallow coseismic slip and amplifies ground accelerations near the accretionary wedge. We then investigate a plausible scenario of a smaller Tohoku-Oki earthquake when its rupture does not reach the accretionary wedge. The sedimentary layer slightly enhances the coseismic slip while the accretionary wedge has almost no influence for the smaller earthquake scenario, but both structures significantly amplify the ground accelerations on the overriding plate. , and By simulating a suite of earthquake scenarios, we suggest that the co-existence of an accretionary wedge and sedimentary layers tend to enhance coseismic slip, but the enhancement effect decreases as the up-dip limit of rupture zones terminates at a larger depth. The numerical simulations were solved using SEM2DPACK _2.3.8 ( http://www.sourceforge.net/projects/sem2d/), and simulation results were visualized by Matlab. This folder includes the input files to reproduce our simulation results and plot scripts.
- Keyword:
- 2011 Tohoku-Oki earthquake, Dynamic rupture simulation, Accretionary wedge, and Sedimentary layer
- Citation to related publication:
- Li, X., & Huang, Y. (2021). The enhancement of coseismic slip and ground motion due to the accretionary wedge and sedimentary layer in the 2011 Tohoku-Oki earthquake (world) [Preprint]. Earth and Space Science Open Archive. https://doi.org/10.1002/essoar.10506336.1
- Discipline:
- Science
-
- Creator:
- Esquivel, Amanda
- Description:
- The survey questions were organized in the following categories: - demographics: age, gender identity, race, ethnicity, and country of birth - education: degree type and date earned, STEM area - employment field, employer information, title, job duties - measures of productivity including research, grant, patents and site/workplace/lab access - work/life balance: responsibilities and duties Questions regarding productivity and work/life balance queried pre and post COVID experiences. Many questions solicited optional comments and the relevant ones are presented as a table.
- Discipline:
- Science
-
- Creator:
- Zurbuchen, Thomas H.
- Description:
- Audification Routines in MATLAB and IDL
- Discipline:
- Science
-
- Creator:
- Yiwen, Mei
- Description:
- The datasets of this archive are produced for a research project on the development of an advanced hydrologic modeling system for the St. Lawrence river basin. The outputted datasets from model simulations are in Netcdf 4 format. The author recommend using the netCDF Operators (NCO) program for data processing. For visualization and plotting, the author recommend using software like MATLAB, Python or R.
- Keyword:
- Hydrologic modeling, reanalysis product, St. Lawrence river, water balance, WRF-Hydro
- Discipline:
- Science
-
Survey Data
User Collection
- Creator:
- Galaty, Michael
- Description:
- All databases, field notebooks, paper maps, GIS files, photographs, and photo descriptions related to the intensive survey, of tracts and tumuli, and the collection of sites have been made available in PASH Deep Blue Data Realm 1. The data are broadly organized by team (A-K). The surveyed land was divided up into “tracts”. Tracts are labeled with team letter and a consecutive number: e.g., A-001, A-002, B-003, C-122, D-035.
- Keyword:
- Archaeology
- Discipline:
- Science
6Works -
Supporting data: Domain-agnostic predictions of nanoscale interactions in proteins and nanoparticles
- Creator:
- Saldinger, Jacob, Raymond, Matt , Elvati, Paolo, and Violi, Angela
- Description:
- The accurate and rapid prediction of generic nanoscale interactions is a challenging problem with broad applications. Much of biology functions at the nanoscale, and our ability to manipulate materials and purposefully engage biological machinery requires knowledge of nano-bio interfaces. While several protein-protein interaction models are available, they leverage protein-specific information, limiting their abstraction to other structures. Here, we present NeCLAS, a general, and rapid machine learning pipeline that predicts the location of nanoscale interactions, providing human-intelligible predictions. Two key aspects distinguish NeCLAS: coarse-grained representations, and the use of environmental features to encode the chemical neighborhood. We showcase NeCLAS with challenges for protein-protein, protein-nanoparticle and nanoparticle-nanoparticle systems, demonstrating that NeCLAS replicates computationally- and experimentally-observed interactions. NeCLAS outperforms current nanoscale prediction models, and it shows cross-domain validity, qualifying as a tool for basic research, rapid prototyping, and design of nanostructures., Software: - To reproduce all-atom molecular dynamics (MD) NAMD is required (version 2.14 or later is suggested). NAMD software and documentation can be found at https://www.ks.uiuc.edu/Research/namd/, - To reproduce coarse-grained MD simulations, LAMMPS (version 29 Sep 2021 - Update 2 or later is suggested). LAMMPS software and documentation can be found at https://www.lammps.org, - To rebuild free energy profiles, the PLUMED plugin (version 2.6) was used. PLUMED software and documentation can be found at https://www.plumed.org/ , and - To generate force matching potentials, the was used the OpenMSCG software was used. OpenMSCG software and documentation can be found at https://software.rcc.uchicago.edu/mscg/
- Keyword:
- Neural Networks, Proteins, Dimensionality Reduction, Nanoparticles, and Coarse-Graining
- Citation to related publication:
- https://www.biorxiv.org/content/10.1101/2022.08.09.503361v2
- Discipline:
- Science
-
- Creator:
- Wittkopp, Patricia J and Massey, Jonathan H
- Description:
- Data provided in this record were collected in the course of studying the genetic basis of differences in wing pigmentation and wing display between Drosophila elegans and Drosophila gunungcola.
- Citation to related publication:
- Massey, J. H., Rice, G. R., Firdaus, A. S., Chen, C.-Y., Yeh, S.-D., Stern, D. L., & Wittkopp, P. J. (2020). Co-evolving wing spots and mating displays are genetically separable traits in Drosophila. Evolution, 74(6), 1098–1111. https://doi.org/10.1111/evo.13990
- Discipline:
- Science
-
- Creator:
- Adam Schneider and Mark Flanner
- Description:
- This dataset contains all data used to generate the figures in The Cryosphere manuscript “Measuring Snow Specific Surface Area with 1.30 and 1.55 micro-meter Bidirectional Reflectance Factors,” by Adam Schneider, Mark Flanner, and Roger De Roo. These data support the theory, calibration, and application of the Near-Infrared Emitting and Reflectance Monitoring Dome (NERD), an instrument engineered to rapidly retrieve surface snow specific surface area in the field. Note that this deposit includes a microCT scan database for natural snowfall samples collected in New Hampshire during 2015-2017, comprised of raw tiff files as well as reconstructions, binarized reconstructions, and some 3D model reconstructions. and Running python scripts generally require that the following packages are installed: NumPy, SciPy, Matplotlib, Pandas, and ipdb (for debugging).
- Keyword:
- Snow specific surface area, Monte Carlo, X-ray micro-computed tomography, SNICAR, Near-Infrared Emitting and Reflectance-Monitoring Dome, Bidirectional reflectance factor, Cryosphere, and 3D
- Discipline:
- Science
-
- Creator:
- Salaree, Amir, Spica, Zack, and Huang, Yihe
- Description:
- The items in this bundle are supporting videos to a study of subsea seismo-acoustics carried out regarding an earthquake in the Persian Gulf. The main data used in the study is a diver's recording of the acoustic waves from the earthquake. The epicenter and topography data used in this study are publicly available as cited in the README.txt file.
- Keyword:
- Seismo-acoustics, Persian Gulf, Divers’ Microphones, Seismic Hazard, Early Warning
- Discipline:
- Science
-
- Creator:
- Gliske, Stephen V and Stacey, William C
- Description:
- This data is part of a large program to translate detection and interpretation of HFOs into clinical use. A zip file is included which contains hfo detections, metadata, and Matlab scripts. The matlab scripts analyze this input data and produce figures as in the referenced paper (note: the blind source separation method is stochastic, and so the figures may not be exactly the same). A file "README.txt" provides more detail about each individual file within the zip file.
- Keyword:
- hfo, high frequency oscillation, ripple, fast ripple, blind source separation, non-negative matrix factorization, and temporal variability
- Discipline:
- Science, Engineering, and Health Sciences
-
- Creator:
- Gliske, Stephen V and Stacey, William C
- Description:
- This data repository includes the quantitative features of high frequency, intracranial EEG along with all necessary scripts to reproduce the figures of the accompanying manuscript.
- Keyword:
- high frequency oscillation, HFO, high frequency activity, and epilepsy
- Citation to related publication:
- (under review)
- Discipline:
- Science, Engineering, and Health Sciences
-
- Creator:
- Mark Flanner
- Description:
- This dataset includes spectrally-resolved optical properties for volcanic ash particles from the 2010 Eyjafjallajökull volcanic eruptions. These properties were used in the climate simulations described by Flanner et al. (2014, doi:10.1002/2014JD021977) to quantify ash radiative forcing from the eruptions.
- Keyword:
- ash, volcano, aerosols, Eyjafjallajökull, climate, and radiative transfer
- Citation to related publication:
- Flanner, M.G., Gardner, A.S., Eckhardt, S., Stohl, A., & Perket, J. (2014). Aerosol radiative forcing from the 2010 Eyjafjallajökull volcanic eruptions. Journal of Geophysical Research: Atmospheres. https://doi.org/10.1002/2014JD021977
- Discipline:
- Science
-
- Creator:
- Singer, Kanakadurga
- Description:
- Supplementary Figure 1. Tissue weights in response to HFD feeding and CL treatment. (A) GWAT weight as % of body weight (B) IWAT weight as % of body weight (C) BAT weight as % of body weight (D) Liver weight as % of body weight. N=7-12 /group; *p<0.05, **p<0.01, ***p<0.005, ****p<0.0001; error bars are SEM. Comparisons of M ND PBS vs F ND PBS are shown as #p<0.05, ##p<0.01, ###p<0.005 and M HFD PBS vs F HFD PBS are shown as &p<0.05, &&p<0.01, &&&p<0.005, &&&&p<0.0001., Supplementary Figure 2. Free glycerol estimation in lean and obese male and female WAT and BAT depot explants with ADRB3 stimulated lipolysis. Free glycerol estimation in lean and obese (A) GWAT (B) IWAT (C) BAT explant tissues. Free glycerol released calculated as fold change over basal conditions in lean and obese (D) GWAT (E) IWAT (F) BAT explant tissues. N=8 /group; *p<0.05, **p<0.01, ***p<0.005, ****p<0.0001; error bars are SEM. Comparisons of M ND PBS vs F ND PBS are shown as #p<0.05, ##p<0.01, ###p<0.005 and M HFD PBS vs F HFD PBS are shown as &p<0.05, &&p<0.01, &&&p<0.005, &&&&p<0.0001., Supplementary Figure 3. Gene expression (A) Akt1 and (B) Glut4 gene expression in obese male and female GWAT with and without ADRB3 stimulation. A.U., arbitrary units, N=5-8; *p<0.05, **p<0.01, ***p<0.005, ****p<0.0001., Supplementary Figure 4. Flow cytometry assessment of ATMs in lean and obese IWAT SVF. Quantitation of (A) IWAT percent ATMs (B) IWAT CD11c+ ATMs (C) IWAT CD11c-ATMs (D) IWAT dendritic cells (DC) numbers, N=7-12/group; *p<0.05, **p<0.01, ***p<0.005, ****p<0.0001. , Supplementary Figure 5. Lipidomic assessment of lipid mediators in obese male and female GWAT. (A) Relative hydroxy fatty acids (FAHFA) (B) Phosphatidylserine (PS) (C) Phosphatidylcholine (PC) (D) Lyso-PC (E) Phosphatidylethanolamine (PE) (F) Phosphatidylglycerol (PG) (G) Phosphatidylinositol (PI) content in obese male and female GWAT with and without CL treatment. N=6/group; *p<0.05, **p<0.01, ***p<0.005, ****p<0.0001., and Curation note: Title of deposit changed from "Supplementary Materials Lipolysis Paper" Dec. 20, 2018 to more closely reflect association with the paper these materials support.
- Discipline:
- Science
-
- Creator:
- Srodawa, Kristy, Cerda, Peter A, Davis Rabosky, Alison R, and Crowe-Riddell, Jenna M
- Description:
- Snake venom research has historically focused on front-fanged species (Viperidae and Elapidae), limiting our knowledge of venom evolution in rear-fanged snakes across their ecologically-diverse phylogeny. Three finger toxins (3FTxs) are a known neurotoxic component in the venoms of some rear-fanged snakes (Colubrinae, Colubridae), but it is unclear how prevalent 3FTxs are both in expression within venom glands and more broadly among colubrine species. Here, we used a transcriptomic approach to characterize the venom expression profiles of four species of colubrine snakes from Neotropics that were dominated by 3FTx expression (in the genera Chironius, Oxybelis, Rhinobothryum, and Spilotes) and reconstructed the gene trees of 3FTxs. Overall, our results highlight the importance of exploring the venoms of understudied species in reconstructing the full evolutionary history of toxins across the tree of life.
- Keyword:
- snake venom, neurotoxin, molecular evolution, gene families, and opisthoglyphous
- Citation to related publication:
- Srodawa, K., Cerda, P.A., Davis Rabosky, A.R., Crowe-Riddell, J.M. Evolution of Three Finger Toxin Genes in Neotropical Colubrine Snakes (Colubridae). Toxins 2023, 15(9), 523; https://doi.org/10.3390/toxins15090523
- Discipline:
- Science
-
- Creator:
- Yue, Min, Kim, Jae Hyun, Evans, Charles R. , Kachman, Maureen, Erb-Downward, John R., D’Souza, Jennifer , Foxman, Betsy, Adar, Sara D. , Curtis, Jeffrey L. , and Stringer, Kathleen A.
- Description:
- This was a small descriptive study to determine whether short chain fatty acids (SCFAs) are detectable in water. It is part of a larger study that assessed the utility of exhaled breath condensate (EBC) as a biofluid for microbiome assays.
- Keyword:
- microbiome, short chain fatty acids, pulmonary, bronchoalveolar lavage fluid, exhaled breath condensate, and water
- Citation to related publication:
- Yue, M., Kim, J. H., Evans, C. R., Kachman, M., Erb-Downward, J. R., D’Souza, J., Foxman, B., Adar, S. D., Curtis, J. L., & Stringer, K. A. (2020). Measurement of Short-Chain Fatty Acids in Respiratory Samples: Keep Your Assay above the Water Line. American Journal of Respiratory and Critical Care Medicine, 202(4), 610–612. https://doi.org/10.1164/rccm.201909-1840LE
- Discipline:
- Science
-
- Creator:
- Carlson, Zachary
- Description:
- Data repository for supplemental data for manuscript. Article and data set are currently under review by publisher. Email for more information.
- Citation to related publication:
- Carlson, Z., Hafner, H., Mulcahy, M., Bullock, K., Zhu, A., Bridges, D., Bernal-Mizrachi, E., & Gregg, B. (2020). Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner. American Journal of Physiology-Endocrinology and Metabolism, 318(5), E600–E612. https://doi.org/10.1152/ajpendo.00473.2019
- Discipline:
- Science
-
- Creator:
- Tronson, Natalie C and Tchessalova, Daria
- Description:
- The main goal of this research was to identify potential molecular pathways that contribute to memory dysregulation and decline that persists long after illness or inflammation. We have previously established a subchronic immune challenge model that results in memory impairments months after the inflammatory challenge. This project aimed to determine whether memory impairments were accompanied by transcriptional dysregulation in memory related brain region (the hippocampus). These data show the differential gene expression as log2fold change (and p-value) in males and females 3 months after immune challenge (Supp Tables 1 and 2); after a subsequent immune challenge (Supp Tables 3 and 4); the differential regulation of genes in males and females (Supp Table 5); genes differentially expressed in the hippocampus of males and females at baseline (Supp Table 6) and the differential regulation of those genes in males and females after immune challenge (Supp Tables 7,8).
- Keyword:
- hippocampus, lipopolysaccharide, differential gene expression, RNA sequencing, neuroimmune, sex differences, learning and memory, and inflammation
- Citation to related publication:
- Tchessalova, D., & Tronson, N. C. (2019). Enduring and sex-specific changes in hippocampal gene expression after a subchronic immune challenge. BioRxiv, 566570. https://doi.org/10.1101/566570
- Discipline:
- Science and Health Sciences
-
- Creator:
- Vani Archaeological Survey
- Description:
- The site of Sakakile (“Place of Beads”) lies 3 km upstream of the village of Sulori, on and around a small promontory on the left bank of the river, formed by a bend in the river and oriented southwest-northeast. This low and level promontory must always have made for a convenient crossing place, and there is now a log bridge running from the right bank of the river to the downstream end of the promontory. South of the promontory is a hill oriented east west from which much of the pottery found on the promontory appears to have eroded. The region around the river crossing is divided topographically into three distinct areas: Kvabiskari (“Place of the Cave/Gorge”), located downstream of the crossing and on the right (north) bank of the river; Sakakile, located on the promontory upstream of the crossing and on the left (south) bank of the river; and Likheti, located upstream of and uphill from Sakakile. Luka Dvalishvili, a resident of Sulori and the owner of the plot of land on the promontory, found a hoard of approximately 700 coins (including a silver Croesid) at Sakakile in the 1970s. At more or less the same time, another local farmer named Generi Paikidze found a bronze axe head here as well. After these chance finds, the Vani excavation team opened up two trenches on northern slope of the hill south of the river, where it slopes down to the low, level promontory of Sakakile. The excavations revealed a mixed assemblage of ceramics eroded from the hill south of the promontory, dating from the 8th-1st century B.C. (Iron Age, Classical, and Hellenistic). The only in-situ pottery assemblage was excavated on the hilltop and dates to the 6th-4th century B.C. Northeast of the hill, in the area where the bronze axe head was supposedly found (dated to the 7th century B.C.), the cobblestone foundation of an apsidal structure was excavated, along with clay tiles and metal implements. The excavation report concludes that occupation on the site began in the 7th-6th century, while the period of most intensive development was the 5th-4th century B.C. We recorded the locations of two trenches from the previous excavations and collected pottery from the eroding northern slope of the hill that forms the southern boundary of the promontory.
- Keyword:
- Iron Age, Late Hellenistic, Hoard, Settlement, and Stray Find
- Citation to related publication:
- In 1984, a chance find of a bronze axe was reported from the area known as Sakakile. In the following year, the Vani excavation team began excavations on the northern slope of the hill south of the river. In 1990 a hoard of 607 coins was found in the village of Sulori. A brief survey of the are was conducted in 2008., Lordkipanidze, O. 1986. Argonavtika da dzveli kolkheti [Argonautics and ancient Colchis]. Tbilisi. pp. 82-83. (In Georgian.), Lordkipanidze, O. D., R. V. Puturidze, D. D. Kacharava, V. A Tolordava, M. S. Pirtskhalava, A. M Chqonia, N. N. Matiashvili, D. V. Akhvlediani, G. Sh. Naridze, and G. A. Inauri. 1987. Raboty Vanskoi ekspeditsii [Work of the Vani archaeological expedition]. Polevye arkheologicheskiye issledovaniya v 1984-85 godakh [Field archaeological investigations in 1984-85]. Tbilisi. pp. 54-55. (In Russian.), Inauri, G. 1990a. Arkheologicheskiye razvedki v s. Sulori [Archaeological explorations in the village of Sulori]. Prichernomorye v VII-V vv. do n. e. Pismennye istochniki i arkheologiya. Materialy V Mezhdunarodnogo simpoziuma po drevnei istorii Prichernomorya. Vani – 1987 [The Black Sea littoral in the 7th-5th centuries B.C. Literary sources and archaeology (Problem of authenticity). Materials of the 5th International symposium dedicated to the problems of the ancient history of the Black Sea littoral. Vani – 1987]. Tbilisi. pp. 276-279. (In Russian.), Inauri, G. 1990b. Le territoire de Vani. Un compte rendu des recherches archéologiques. Le Pont-Euxin vu par les grecs. Sources écrites et archéologique. Symposium de Vani (Colchide), Septembre-Octobre 1987, Otar Lordkipanidze et Pierre Lévêque, ed. Tea Khartchilava et Evelyne Geny. Centre de Recherches d’Histoire Ancienne, Vol. 100. Paris: Annales Littéraires de l’Université de Besançon. pp. 249-252. (In French.), Lébanidzé, L. 1999. Le trésor monétaire de Sulori. La Mer Noire zone de contacts. Actes du VIIe Sympsium de Vani (Colchide) – 26-30.IX.1994. Paris. p. 155-158., Lordkipanidze, Otar. 2002. Dzeli kartuli civilizaciis sataveebtan [The sources of ancient Georgian civilization]. Tbilisi. pp. 206-7. (In Georgian.), and Kharabadze, S. 2008. “Vanis Qveq’nis” Arqeologiuri Ruk’a (dzv.ts. VIII – akh.ts. III ss.). (Archaeological Map of the Vani Land, 8th Century BC – 3rd Century AD). Tsardgenilia Doqt’oris Ak’ademiuri Khariskhis Mosap’oveblad. Saqartvelos T’eqnik’uri Universit’et’i. Tbilisi, 0175, Saqartvelo. Seqt’emberi. p. 20. (In Georgian with an English summary.)
- Discipline:
- Science and Humanities