Now showing items 21-30 of 52
Raman spectroscopy monitoring of the cellular activities of a tissue-engineered ex vivo produced oral mucosal equivalent
(John Wiley & Sons, Ltd., 2011-02)
To ensure quality control and assurance in tissue engineering, noninvasive, real-time and aseptic evaluation of cell-based devices is required before product release. In this study, Raman spectroscopy was applied to monitor ...
Plasma Discharges in Gas Bubbles in Liquid Water: Breakdown Mechanisms and Resultant Chemistry.
(2015)
The use of atmospheric pressure plasmas in gases and liquids for purification of liquids has been investigated by numerous researchers, and is highly attractive due to their strong potential as a disinfectant and sterilizer. ...
Picturing the Membrane‐assisted Choreography of Cytochrome P450 with Lipid Nanodiscs
(Springer Science & Business MediaWiley Periodicals, Inc., 2018-10-19)
Cytochrome P450, a family of monooxygenase enzymes, is organized as a catalytic metabolon, and requires enzymatic partners as well as environmental factors that tune its complex dynamic activity. P450 and its reducing ...
Bone quality assessment of osteogenic cell cultures by Raman microscopy
(Humana PressWiley Periodicals, Inc., 2019-03)
The use of autologous stem/progenitor cells represents a promising approach to the repair of craniofacial bone defects. The calvarium is recognized as a viable source of stem/progenitor cells that can be transplanted in ...
Addressing the Requirements of High‐Sensitivity Single‐Molecule Imaging of Low‐Copy‐Number Proteins in Bacteria
(Wiley Periodicals, Inc., 2016-05-18)
Single‐molecule fluorescence super‐resolution imaging and tracking provide nanometer‐scale information about subcellular protein positions and dynamics. These single‐molecule imaging experiments can be very powerful, but ...
The Role of Topological Constraints in RNA Tertiary Folding and Dynamics.
(2014)
Functional RNA molecules must fold into highly complex three-dimensional (3D) structures and undergo precise structural dynamics in order to carry out their biological functions. However, the principles that govern RNA 3D ...
Methodological Advances for Drug Discovery and Protein Engineering
(2018)
Designing and engineering molecules that have specified properties not only test our understanding of nature but also play an important role in improving both human health and industrial productivity. Two such examples are ...
Modifying Single-Molecule Fluorescence with a Plasmonic Optical Antenna: Theory, Methodology, and Measurement
(2018)
Nanophotonics is the study and technological application of light on the nanometer scale. This dissertation brings together two disparate branches of nanophotonics: plasmonics and single-molecule super-resolution microscopy. ...
Mapping, Tracking and Modeling the Movements of Single Membrane-Bound Transcription Activator Proteins in Live Vibrio cholerae.
(2014)
Cholera has been known since ancient times, yet there is still no cure. Vibrio cholerae bacteria cause cholera by producing cholera toxin. Cholera toxin production is regulated by the protein ToxT, which itself is regulated ...
Ultrafast Hydration Dynamics Near Extended Macromolecular Interfaces
(2019)
Liquid water is arguably the most complex, but interesting chemical, enabling development and sustenance of life. The tetrahedral geometry of the water molecule allows the formation of a dense network of hydrogen bonds ...