Now showing items 351-360 of 408
Real time volumetric MRI for 3D motion tracking via geometry-informed deep learning
(IEEEWiley Periodicals, Inc., 2022-09)
PurposeTo develop a geometry-informed deep learning framework for volumetric MRI with sub-second acquisition time in support of 3D motion tracking, which is highly desirable for improved radiotherapy precision but hindered ...
Energy layer optimization via energy matrix regularization for proton spot-scanning arc therapy
(Wiley Periodicals, Inc., 2022-09)
PurposeSpot-scanning arc therapy (SPArc) is an emerging proton modality that can potentially offer a combination of advantages in plan quality and delivery efficiency, compared with traditional IMPT of a few beam angles. ...
Extending the Continual Reassessment Method to accommodate step‐up dosing in Phase I trials
(Wiley Periodicals, Inc., 2022-09-10)
Feasibility of ultrasound tomography–guided localized mild hyperthermia using a ring transducer: Ex vivo and in silico studies
(University of OxfordWiley Periodicals, Inc., 2022-09)
BackgroundAs of 2022, breast cancer continues to be the most diagnosed cancer worldwide. This problem persists within the United States as well, as the American Cancer Society has reported that ∼12.5% of women will be ...
Clinical xenotransplantation seems close: Ethical issues persist
(WHOWiley Periodicals, Inc., 2022-06)
Scientific barriers that have prevented successful xenotransplantation are being breached, yet many ethical issues remain. Some are broad issues that accompany the adoption of novel and expensive technologies, and some are ...
Suicidal ideation and sobriety: Should acute alcohol intoxication be taken into account for psychiatric evaluation?
(Substance Abuse and Mental Health Services AdministrationWiley Periodicals, Inc., 2022-07)
BackgroundWhen evaluating an emergency department (ED) patient who presents with suicidal ideation, it is a common practice to wait until the patient’s ethanol level is known or calculated to be less than 80 mg/dl to ...
Improving large-scale estimation and inference for profiling health care providers
(Massachusetts Medical SocietyWiley Periodicals, Inc., 2022-07-10)
Provider profiling has been recognized as a useful tool in monitoring health care quality, facilitating inter-provider care coordination, and improving medical cost-effectiveness. Existing methods often use generalized ...
Genetic interaction between Scn8a and potassium channel genes Kcna1 and Kcnq2
(University of WashingtonWiley Periodicals, Inc., 2022-10)
Voltage-gated sodium and potassium channels regulate the initiation and termination of neuronal action potentials. Gain-of-function mutations of sodium channel Scn8a and loss-of-function mutations of potassium channels ...
Semiparametric analysis of a generalized linear model with multiple covariates subject to detection limits
(John Wiley & Sons, Inc., 2022-10-30)