Now showing items 11-20 of 562
Impact of sarcopenia on treatment tolerance in United States veterans with diffuse large B‐cell lymphoma treated with CHOP‐based chemotherapy
(Wiley Periodicals, Inc.IARC Press, 2016-10)
Haplotype variation and genotype imputation in African populations
(Wiley Subscription Services, Inc., A Wiley Company, 2011-12)
Sub‐Saharan Africa has been identified as the part of the world with the greatest human genetic diversity. This high level of diversity causes difficulties for genome‐wide association (GWA) studies in African populations—for ...
Hepatic Sel1L‐Hrd1 ER‐associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH
(Wiley Periodicals, Inc., 2018-11-15)
Fibroblast growth factor 21 (Fgf21) is a liver‐derived, fasting‐induced hormone with broad effects on growth, nutrient metabolism, and insulin sensitivity. Here, we report the discovery of a novel mechanism regulating Fgf21 ...
Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels
(Wiley Periodicals, Inc., 2017-12)
The accuracy of genotype imputation depends upon two factors: the sample size of the reference panel and the genetic similarity between the reference panel and the target samples. When multiple reference panels are not ...
Highlights of B/D‐HPP and HPP Resource Pillar Workshops at 12th Annual HUPO World Congress of Proteomics
(Wiley Periodicals, Inc., 2014-05)
Time course of tinnitus development following noise exposure in mice
(Wiley Subscription Services, Inc., A Wiley Company, 2012-07)
Gap‐induced prepulse inhibition of acoustic startle (GPIAS) has been used in rats and mice to study the problem of tinnitus. The current study demonstrates that similar methods can be used to study the temporal development ...
Microfluidic Reduction of Osmotic Stress in Oocyte and Zygote Vitrification.
(2014)
Microfluidic cryoprotectant exchange enables vitrification of murine zygotes with superior morphology as indicated by a smoother cell surface and higher developmental competence compared to conventional methods. Bovine ...
Effects of hydroxyurea on CNV induction in the mouse germline
(John Wiley & Sons, Inc., 2018-10)
Rareâ variant association tests in longitudinal studies, with an application to the Multiâ Ethnic Study of Atherosclerosis (MESA)
(Wiley Periodicals, Inc.Springer New York, 2017-12)
Over the past few years, an increasing number of studies have identified rare variants that contribute to trait heritability. Due to the extreme rarity of some individual variants, geneâ based association tests have been ...