Now showing items 141-150 of 158
Tunable laser Stark-difference spectra of CD3OH
(Elsevier, 1981-09)
We present Doppler resolution limited spectra of the P(J) and R(J) multiplets for J [less, double equals] 10 of the 10-[mu]m C---O stretch band of 12CD316OH using a tunable diode laser. Relative frequencies within the ...
Methodological Advances for Drug Discovery and Protein Engineering
(2018)
Designing and engineering molecules that have specified properties not only test our understanding of nature but also play an important role in improving both human health and industrial productivity. Two such examples are ...
Quantum Inspired Machine Learning Algorithms for Adaptive Radiotherapy
(2021)
Adaptive radiotherapy (ART) refers to the modification of radiotherapy treatment plans in response to patient anatomical and physiological changes over the course of treatment and has been recognized as an important step ...
Biophysical Approaches to Target Protein-Protein Interactions of Epigenetic Complexes by Small-Molecule Inhibitors
(2019)
Innumerable biological systems rely on Protein-Protein Interactions (PPIs) to govern basal physiological processes. Deregulation of PPIs is implicated in various human diseases, and PPIs have thus been frequently promoted ...
Local to Global Multi-Scale Multimedia Modeling of Chemical Fate and Population Exposure
(2017)
To assess environmental and human exposure to chemical emissions, two types of approaches are available: 1. intermediate- to high-resolution, substance/location-specific analyses, and 2. lower resolution, less specific ...
Nanopores with Fluid Walls for Characterizing Proteins and Peptides.
(2012)
Nanopore-based, resistive-pulse sensing is a simple single-molecule technique, is label free, and employs basic electronic recording equipment. This technique shows promise for rapid, multi-parameter characterization of ...
Acoustically-Responsive Scaffolds: Control of Growth Factor Release for Tissue Regeneration Using Ultrasound
(2017)
Administration of exogenous growth factors (GFs) is a proposed method of stimulating tissue regeneration. Conventional administration routes, such as at-site or systemic injections, have yielded problems with efficacy ...
The Effects of Disruption of Synaptic Signaling on Neuronal Networks
(2020)
The brain is an organ that acts as the conductor of an orchestra – it governs all vital body functions and assures that all organs operate in harmony. Moreover, it plays a crucial role in various tasks such as memory ...
Membrane Curvature During Cell Migration
(2020)
Biological membranes serve as a physical barrier of cell and organelles. In addition, as biological membranes house numerous proteins, they also act as signaling hubs involved in the regulation of a wide array of cellular ...
Modeling Dose-Function Response and Toxicity Pathways in Non-Small Cell Lung Cancer Patients Undergoing Radiation Treatment
(2021)
Radiotherapy is currently the standard of care for treating NSCLC patients, and while technological advancements in the field continue to improve our ability to successfully treat these patients, serious side-effects, i.e. ...