Now showing items 1-10 of 950
Transgene-mediated GDNF expression enhances synaptic connectivity and GABA transmission to improve functional outcome after spinal cord contusion
(Blackwell Publishing Ltd, 2010-04)
J. Neurochem. (2010) 10.1111/j.1471-4159.2010.06593.xGlial cell line-derived trophic factor (GDNF) is a peptide with pleiotropic survival and growth-promoting effects on neurons. We found that intraspinal injection of a ...
Inhibition of Vesicular Glutamate Uptake by Rose Bengal-Related Compounds: Structure–Activity Relationship
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2005-03)
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission. We have previously shown that Rose Bengal, a polyhalogenated fluorescein analog, is a potent inhibitor of glutamate uptake ...
Cerebellar gray and white matter volume and their relation with age and manual motor performance in healthy older adults
(SpringerWiley Periodicals, Inc., 2015-06)
ObjectivesFunctional neuroimaging and voxel‐based morphometry studies have confirmed the important role of the cerebellum in motor behavior. However, little is known about the relationship between cerebellar gray (GMv) and ...
Number of contractions to maintain mass and force of a denervated rat muscle
(Wiley Subscription Services, Inc., A Wiley Company, 2004-07)
Within 5 weeks, denervated extensor digitorum longus (EDL) muscles of rats lose 66% of mass, 91% of force, and 76% of fiber cross-sectional area (CSA). We previously determined the parameters of electrical stimulation for ...
Cellular expression of Midkine-a and Midkine-b during retinal development and photoreceptor regeneration in zebrafish
(Wiley Subscription Services, Inc., A Wiley Company, 2009-05-01)
In the retina of adult teleosts, stem cells are sustained in two specialized niches: the ciliary marginal zone (CMZ) and the microenvironment surrounding adult MÜller glia. Recently, MÜller glia were identified as the ...
Imaging Changes after Stereotactic Radiosurgery of Primary and Secondary Malignant Brain Tumors
(Kluwer Academic Publishers; Springer Science+Business Media, 2002-01)
After radiosurgery of malignant tumors, it can be difficult to discriminate between transient treatment effects, radiation necrosis, and tumor progression on post-treatment imaging. Misinterpretation of an enlarging lesion ...
Functional characterization of mouse α4β2 nicotinic acetylcholine receptors stably expressed in HEK293T cells
(Blackwell Science Ltd, 2004-12)
Mouse α4β2 nicotinic acetylcholine receptors (nAchRs) were stably expressed in HEK293T cells. The function of this stable cell line, termed mmα4β2, was assessed using an aequorin-based luminescence method that measures ...
Opioid Regulation of Pair Bonding in the Socially Monogamous Prairie Vole.
(2014)
The socially monogamous prairie vole is an excellent animal model for studies of the neurobiology of selective social attachment. Here, we have demonstrated that monogamous bonds are formed and maintained by a balance ...
Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy
(Wiley Periodicals, Inc.WHO, 2019-08)
Simultaneous Multislice Functional Magnetic Resonance Imaging.
(2016)
Functional magnetic resonance imaging (fMRI) is a valuable tool for mapping brain activity in many fields. Since functional activity is determined by temporal signal changes, undesired fluctuations from physiological motion ...