Now showing items 21-30 of 444
Oligoribonucleotides with 2′‐O‐(tert‐Butyldimethylsilyl) Groups
(Wiley Periodicals, Inc.IRL Press,, 2000-07)
The chemical synthesis of oligoribonucleotides on solid support is routinely performed via the phosphoramidite method. However, the additional 2‐OH function of the ribofuranosyl sugar requires suitable protection during ...
Determination of Binding Mode: Intercalation
(Academic PressWiley Periodicals, Inc., 2000-02)
A small molecule can be assumed to bind to DNA by intercalation between base pairs if it causes lengthening and unwinding of the DNA helix and undergoes changes in its spectral properties, such as DNA‐induced hypochromism ...
Early events of Bacillus anthracis germination identified by time-course quantitative proteomics
(WILEY-VCH Verlag, 2006-10)
Germination of Bacillus anthracis spores involves rehydration of the spore interior and rapid degradation of several of the protective layers, including the spore coat. Here, we examine the temporal changes that occur ...
Cellular Delivery of Locked Nucleic Acids (LNAs)
(Wiley Periodicals, Inc., 2002-06)
Locked nucleic acids (LNAs) are RNA derivatives that have an O‐methylene linkage between the 2 and 4 positions of the ribose. This leads to exceptionally high‐affinity binding to complementary sequences. They are synthesized ...
Ring-opening polymerization of epoxy end-terminated poly(ethylene oxide) as a route to highly crosslinked materials with exceptional swelling behavior (II)
(John Wiley & Sons, Ltd., 2007-08)
Highly swellable poly(ethylene oxide) (PEO) gels were prepared by anionic ring-opening polymerization of diepoxy end-capped PEO (3400 g mol −1 ) and PEO (8000 g mol −1 ) using dianionic glycerol and glycolic acid initiators ...
Focus on function: Single molecule RNA enzymology
(Wiley Subscription Services, Inc., A Wiley Company, 2007-12-05)
The ability of RNA to catalyze chemical reactions was first demonstrated 25 years ago with the discovery that group I introns and RNase P function as RNA enzymes (ribozymes). Several additional ribozymes were subsequently ...
Low-Temperature SCR of NO with NH 3 over USY-Supported Manganese Oxide-Based Catalysts
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2003-04)
A series of catalysts of manganese oxide, manganese–cerium and iron–manganese oxide supported on USY (ultra-stable Y zeolite) were studied for the low-temperature selective catalytic reduction (SCR) of NO with ammonia in ...
Nickel and Its Surprising Impact in Nature . Metal Ions in Life Science, Bd. 2. Herausgegeben von Astrid Sigel , Helmut Sigel und Roland K. 14O. Sigel .
(WILEY-VCH Verlag, 2008-01-18)
No Abstract
Cluster distance geometry of polypeptide chains
(Wiley Subscription Services, Inc., A Wiley Company, 2004-07-30)
Distance geometry has been a broadly useful tool for dealing with conformational calculations. Customarily each atom is represented as a point, constraints on the distances between some atoms are obtained from experimental ...
Base Composition Analysis of Nucleosides Using HPLC
(Applied Biosystems,Wiley Periodicals, Inc., 2000-07)
In this protocol, nuclease digestion of an oligonucleotide is followed by dephosphorylation and HPLC analysis of the monomers on a reversed‐phase C18 column. This method can be used to detect and quantitate a wide variety ...