Now showing items 3111-3120 of 3121
Bayesian Learning of Structured Covariances, with Applications to Cancer Data
(2023)
The identification of scientifically-driven dependence structures is of interest across many biomedical domains. Examples include tree- and graph-based structures manifesting themselves in precision medicine and genomic ...
Socio-Contextual and Multi-Omic Associations with Cognitive Function and Structural Brain Measures in Older African Americans
(2023)
Dementia affects approximately 1 in 10 persons aged 65 years and older in the U.S., and African Americans (AA) are more likely to develop dementia compared to European Americans (EA). However, the underlying molecular ...
The impact of community midwives on maternal healthcare utilization
(Wiley Periodicals, Inc.Advancing Partners & Communities, 2023-03)
Globally 800 women die every day from preventable causes related to pregnancy and childbirth. One of the major reasons for high maternal mortality ratios in many developing countries is the low proportion of births attended ...
The local health impacts of natural resource booms
(Wiley Periodicals, Inc.World Bank, 2023-02)
This paper uses novel micro-data on natural resources and administrative health data in Brazil to study how economic booms in minerals affect health at birth. By implementing a reduced-form estimation of shift-share research ...
Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin-expressing interneurons, and inhibitory function in the auditory cortex
(John Wiley & Sons, Inc., 2023-02)
For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination focused primarily on excitatory cells. Recent evidence showed that axons of inhibitory neurons in the neocortex are ...
Robust causal inference of drug-drug interactions
(John Wiley & Sons, Inc., 2023-03-30)
Dynamics of Influenza Protection and Infection: Implications for Vaccination Development
(2022)
Influenza is a major contributor to respiratory morbidity and mortality worldwide and is a particular concern for high-risk populations including children. Although influenza has been studied for over 100 years, major gaps ...
Body composition and mortality in men receiving prostate radiotherapy: A pooled analysis of NRG/RTOG 9406 and NRG/RTOG 0126
(Wiley Periodicals, Inc., 2023-03-01)
PurposeTo validate the association between body composition and mortality in men treated with radiation for localized prostate cancer (PCa). Secondarily, to integrate body composition as a factor to classify patients by ...
Prevention Strategies for Gynecologic Cancers
(2022)
This dissertation focused on prevention strategies for ovarian and cervical cancers. Primary prevention of ovarian cancer was explored in Aim 1 using data from the Ovarian Cancer Association Consortium (OCAC; 7,743 cases; ...
CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study
(Wiley Periodicals, Inc., 2023-03-01)
BackgroundCyclin E1 (CCNE1) is a potential predictive marker and therapeutic target in tubo-ovarian high-grade serous carcinoma (HGSC). Smaller studies have revealed unfavorable associations for CCNE1 amplification and ...