Now showing items 1-10 of 10
Evaluation of ( E )-2′-deoxy-2′-(fluoromethylene)cytidine on the 9L rat brain tumor model using MRI
(John Wiley & Sons, Ltd., 2003-04)
( E )-2′-deoxy-2′-(fluoromethylene)cytidine (FMdC), was evaluated as a potential treatment for malignant gliomas using the rat 9L brain tumor model. FMdC was shown to be an effective inhibitor of cell proliferation in ...
HgCdTe Auger-Suppressed Infrared Detectors Under Non-Equilibrium Operation.
(2009)
A nearly universal goal for infrared photon detection systems is to increase their operating temperature without sacrificing performance. The limiting factor for cooling requirements is the dark current in the detector ...
Proton and sodium MRI assessment of emerging tumor chemotherapeutic resistance
(John Wiley & Sons, Ltd., 2006-12)
The ultimate goal of any cancer therapy is to target the elimination of neoplastic cells. Although newer therapeutic strategies are in constant development, therapeutic assessment has been hampered by the inability to ...
Diffusion imaging for evaluation of tumor therapies in preclinical animal models
(Springer-Verlag; ESMRMB, 2004-12)
The increasing development of novel targeted therapies for treating solid tumors has necessitated the development of technology to determine their efficacy in preclinical animal models. One such technology that can ...
Quantitative characterization of hemodynamic properties and vasculature dysfunction of high-grade gliomas
(John Wiley & Sons, Ltd., 2007-10)
Aberrations in tumor and peritumoral vasculature may not be distinguishable by cerebral blood flow (CBF) or cerebral blood volume (CBV) alone. The relationships between CBF and CBV were examined to estimate vasculature-specific ...
Magnetization transfer effects on the efficiency of flow-driven adiabatic fast passage inversion of arterial blood
(John Wiley & Sons, Ltd., 2007-12)
Continuous arterial spin labeling experiments typically use flow-driven adiabatic fast passage inversion of the arterial blood water protons. In this article, we measure the effect of magnetization transfer in blood and ...
Laser Fabrication of High-K Dielectrics for High Current Cathodes.
(2008)
Triple point, defined as the junction of metal, dielectric, and vacuum, is the location where electron emission is favored in the presence of a sufficiently strong electric field. Recent work at the University of Michigan ...
Electron Field Emission from Boron Nitride Thin Films.
(2008)
A systematic study of electron field emission from boron nitride thin films is presented, establishing nanostructured thin film cubic boron nitride (cBN) as a robust and chemically inert material with a low effective ...
Optical and Magnetic Manipulation of Hybrid Micro and Nanoparticle Sensors.
(2008)
Microparticles and nanoparticles have been used in a wide variety of applications ranging from biomedical to optical and electronic technologies. The microscopic and mesoscopic size scale of single particles makes them ...
Few-Cycle and Sub-Cycle Metrology for the Characterization of High Harmonics.
(2009)
The rapid advances in the generation of ultra-short optical pulses in recent decades have often outstripped the ability of metrologists to accurately measure the pulses' temporal profiles. With each reduction in pulse ...