Now showing items 11-20 of 654
Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels
(Wiley Periodicals, Inc., 2017-12)
The accuracy of genotype imputation depends upon two factors: the sample size of the reference panel and the genetic similarity between the reference panel and the target samples. When multiple reference panels are not ...
Highlights of B/D‐HPP and HPP Resource Pillar Workshops at 12th Annual HUPO World Congress of Proteomics
(Wiley Periodicals, Inc., 2014-05)
Revisiting the Response Mechanism of Polymeric Membrane Based Heparin Electrodes
(WILEY‐VCH Verlag, 2012-01)
Potentiometric membrane electrodes that respond to heparin and other polyanions were introduced in the early 1990s. Herein, the mechanism of polymer membrane electrode type heparin sensors is revisited. The extraction/diffusion ...
Effects of hydroxyurea on CNV induction in the mouse germline
(John Wiley & Sons, Inc., 2018-10)
Retrievable hydrogels for ovarian follicle transplantation and oocyte collection
(American Cancer SocietyWiley Periodicals, Inc., 2018-08)
Cancer survivorship rates have drastically increased due to improved efficacy of oncologic treatments. Consequently, clinical concerns have shifted from solely focusing on survival to quality of life, with fertility ...
Rareâ variant association tests in longitudinal studies, with an application to the Multiâ Ethnic Study of Atherosclerosis (MESA)
(Wiley Periodicals, Inc.Springer New York, 2017-12)
Over the past few years, an increasing number of studies have identified rare variants that contribute to trait heritability. Due to the extreme rarity of some individual variants, geneâ based association tests have been ...
Mechanism of Nucleotide Flipping by Human Alkyladenine DNA Glycosylase.
(2014)
Nucleotide flipping is the phenomenon whereby a nucleotide in DNA is rotated 180 degrees out of the double helix into an extrahelical position. This event is critical to many biological processes in which enzymes need ...
Molecular Electron Mircroscopy of Signaling Protein Complexes.
(2013)
G protein-coupled receptors (GPCRs) are the primary signal transduction units responsible for the communication between cells and their environment. Thus, GPCRs are involved in every aspect of human physiology and are ...