Now showing items 1981-1990 of 1999
Lip service: Histological phenotypes correlate with diet and feeding ecology in herbivorous pacus
(John Wiley & Sons, Inc., 2023-02)
Complex prey processing requires the repositioning of food between the teeth, as modulated by a soft tissue appendage like a tongue or lips. In this study, we trace the evolution of lips and ligaments, which are used during ...
Assessment of renal outcome following therapy in monoclonal immunoglobulin deposition disease: Emphasizing the need for a consensus approach
(John Wiley & Sons, Inc., 2023-03)
Monoclonal immunoglobulin deposition disease (MIDD), often associated with plasma cell dyscrasias, predominantly affects the kidneys. In this disease, hematologic response (HR) to treatment can be reliably assessed by ...
The impact of community midwives on maternal healthcare utilization
(Wiley Periodicals, Inc.Advancing Partners & Communities, 2023-03)
Globally 800 women die every day from preventable causes related to pregnancy and childbirth. One of the major reasons for high maternal mortality ratios in many developing countries is the low proportion of births attended ...
Intergenerational arsenic exposure on the mouse epigenome and metabolic physiology
(John Wiley & Sons, Inc., 2023-02)
Inorganic arsenic (iAs) is one of the largest toxic exposures to impact humanity worldwide. Exposure to iAs during pregnancy may disrupt the proper remodeling of the epigenome of F1 developing offspring and potentially ...
The local health impacts of natural resource booms
(Wiley Periodicals, Inc.World Bank, 2023-02)
This paper uses novel micro-data on natural resources and administrative health data in Brazil to study how economic booms in minerals affect health at birth. By implementing a reduced-form estimation of shift-share research ...
Super-Strong Hydrogel Composites Reinforced with PBO Nanofibers for Cartilage Replacement
(Wiley Periodicals, Inc.Imperial College Press, 2023-02)
Cartilage replacement materials exhibiting a set of demanding properties such as high water content, high mechanical stiffness, low friction, and excellent biocompatibility are quite difficult to achieve. Here, ...
Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin-expressing interneurons, and inhibitory function in the auditory cortex
(John Wiley & Sons, Inc., 2023-02)
For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination focused primarily on excitatory cells. Recent evidence showed that axons of inhibitory neurons in the neocortex are ...
Robust causal inference of drug-drug interactions
(John Wiley & Sons, Inc., 2023-03-30)
Engineering Multifunctional Nanoparticles: Applied Nanoscale Therapeutics
(2022)
Decades of research towards the development of nanomedicines have, to date, yielded minimal
clinical impact. Focused particularly on the treatment of cancer, the relatively low
number of pursued technologies to reach the ...
Targeting MCL-1 and BCL-2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non-Hodgkin lymphoma: Results from preclinical models and a Phase Ib study
(John Wiley & Sons, Inc., 2023-03)
The treatment of patients with relapsed or refractory lymphoid neoplasms represents a significant clinical challenge. Here, we identify the pro-survival BCL-2 protein family member MCL-1 as a resistance factor for the BCL-2 ...