Now showing items 3431-3440 of 3521
Methodological Advances for Drug Discovery and Protein Engineering
(2018)
Designing and engineering molecules that have specified properties not only test our understanding of nature but also play an important role in improving both human health and industrial productivity. Two such examples are ...
A Systematic Informatics Approach to Synthetic Chemistry
(2023)
The navigation of chemical space through synthesis is a core principle behind drug discovery. Traditional medicinal chemistry programs rely on a few, well-developed reactivities to create pharmacophore derivatives and ...
Inverse Design and Analysis of Crystallization Pathways of Colloidal Systems
(2019)
The ability to produce particles on the nano-scale that self-assemble into soft materials with specifically targeted properties is a promising avenue for a completely new class of materials with novel applications. New ...
Data-Driven Modeling of Compressible Reacting Flow Using Hardware-Oriented Algorithms
(2022)
High-fidelity numerical simulations of combustion processes in next-generation hypersonic propulsion devices (including, but not limited to, rotating detonation engines and scramjets) play a crucial role in enabling robust ...
Understanding the Optical and Photophysical Properties of Organic and Hybrid Macromolecules and Polymers for Solar Cell Application
(2021)
Organic solar cell materials represent a better sustainable alternative relative to inorganic materials in terms of lower cost, ease of large-scale processing, better absorptivity, ease of tunability, and unique flexibility ...
Synthesis and Characterization of Microporous Coordination Polymers as Adsorbents for CO2 Capture.
(2012)
The accumulation of CO2 in the Earth’s atmosphere is an important environmental issue, and coal-fired power plants are significant contributors to anthropogenic CO2 emissions. The capture of CO2 from these facilities via ...
Investigations into Asphaltene Deposition, Stability, and Structure.
(2013)
Asphaltenes are known to cause a number of petroleum production, transportation and processing concerns. The overarching goal of this body of work was to elucidate the fundamental structure and behavior of asphaltenes for ...
Folate Binding Protein as a Therapeutic Natural Nanotechnology
(2018)
Serum proteins interact with small molecules and nanoparticles in blood, resulting in protein coronas. Protein coronas influence the bioidentity of the molecules and nanoparticles, playing critical roles in biotransport, ...
Continuum-Scale Modeling of Rechargeable Batteries
(2020)
During the operation of a rechargeable battery, the electrochemical reactions occur at the interface between the electrolyte and the active material in the electrode. The electrochemical performance of such batteries is ...
Localized Tolerance and Development of an Alternative Transplant Site to Treat Type 1 Diabetes
(2017)
Islet transplantation is an attractive treatment for type 1 diabetes (T1D) to restore the body’s ability to endogenously produce insulin and rapidly respond to changes in blood glucose levels. Current clinical strategies ...