Now showing items 211-220 of 231
Utility based approach in individualized optimal dose selection using machine learning methods
(Wiley Periodicals, Inc.MIT Press, 2022-07-20)
The goal in personalized medicine is to individualize treatment using patient characteristics and improve health outcomes. Selection of optimal dose must balance the effect of dose on both treatment efficacy and toxicity ...
Self-reporting and screening: Data with right-censored, left-censored, and complete observations
(Wiley Periodicals, Inc.Springer, 2022-08-15)
A multivariate parametric empirical Bayes screening approach for early detection of hepatocellular carcinoma using multiple longitudinal biomarkers
(SpringerWiley Periodicals, Inc., 2022-06-15)
Split and combine simulation extrapolation algorithm to correct geocoding coarsening of built environment exposures
(North American Association of Central Cancer RegistriesWiley Periodicals, Inc., 2022-05-20)
Extending the Continual Reassessment Method to accommodate step‐up dosing in Phase I trials
(Wiley Periodicals, Inc., 2022-09-10)
Improving large-scale estimation and inference for profiling health care providers
(Massachusetts Medical SocietyWiley Periodicals, Inc., 2022-07-10)
Provider profiling has been recognized as a useful tool in monitoring health care quality, facilitating inter-provider care coordination, and improving medical cost-effectiveness. Existing methods often use generalized ...
Semiparametric analysis of a generalized linear model with multiple covariates subject to detection limits
(John Wiley & Sons, Inc., 2022-10-30)
Design and Analysis of Sequential Randomized Trials with Applications to Mental Health and Online Education
(2019)
Dynamic treatment regimes, also called adaptive interventions, guide sequential treatment decision-making in a variety of fields, including healthcare and education. Dynamic treatment regimes accommodate differences between ...
Reducing Maternal Mortality and Morbidity in Michigan: A Mixed Methods Analysis of the Impact of an Obstetric Hemorrhage Patient Safety Bundle
(2022)
The United States has the highest rate of maternal mortality despite outspending all other resource-rich countries in per-capita reproductive health care. Contributing to this problem are a combination of factors including ...