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- Creator:
- Cao, Yinyin, Lawson, Benn, and Pil, Frits K.
- Description:
- As part of a larger research study on social sustainability and human rights, this research examines the supplier codes of conduct lead firms adopt to achieve their social supply chain sustainability goals.
- Keyword:
- social sustainability, human rights, and supplier codes of conduct
- Citation to related publication:
- Cao, Y., Lawson, B., & Pil, F. K. (2023). Social sustainability and human rights in global supply chains, International Journal of Operations & Production Management, Vol. ahead-of-print No. ahead-of-print. https://doi.org/10.1108/IJOPM-10-2022-0670.
- Discipline:
- Business
-
- Creator:
- McCuen, Brett A.
- Description:
- We present a comprehensive statistical analysis of high-frequency transient-large-amplitude (TLA) magnetic perturbation events that occurred at 12 high-latitude ground magnetometer stations throughout solar cycle 24 from 2009 to 2019. TLA signatures are defined as one or more second-timescale dB/dt interval with magnitude ≥ 6 nT/s within an hour event window. This study characterizes high-frequency TLA events based on their spatial and temporal behavior as well as relation to auroral substorms, geomagnetic storm phases and nighttime geomagnetic disturbance events events (GMD). We show that TLA events occur primarily at nighttime and solely in the high-latitude region above 60 degrees geomagnetic latitude. The largest TLA events occurred more often in the declining phase of the solar cycle when solar wind velocity was higher and ring current activity was lower, suggesting association to high-speed flows caused by coronal holes and subsequent corotating interaction regions reaching Earth. TLA perturbations often occurred preceding or within the most extreme nighttime geomagnetic disturbance (GMD) events with 5-10 minute timescales, but the TLA intervals were often even more localized than the ~300 km effective radius of GMDs: occurring at only some of the stations at which GMDs occurred. We show that TLA-related GMD events can result from dipolarization fronts in the magnetotail and fast flows toward Earth and are closely temporally associated to poleward boundary intensifications (PBI) and auroral streamers. The highly localized behavior and connection to the most extreme GMD events suggests that TLA intervals are a ground manifestation of the features within rapid and complex ionospheric structures that can drive GICs.
- Keyword:
- geomagnetic field, high frequency, space weather, transient-large-amplitude, TLA, high frequency dB/dt, dB/dt search algorithm
- Citation to related publication:
- McCuen, B. A., Moldwin, M. B., Engebretson, M. J., Weygand, J. G., Nishimura, Y. (2023). A Statistical Analysis of High-frequency Transient-Large-Amplitude Geomagnetic Disturbance. [To be submitted to] Journal of Geophysical Research: Space Physics
- Discipline:
- Science
-
- Creator:
- Brennan, Jonathan R.
- Description:
- These files contain the raw data and processing parameters to go with the paper "Hierarchical structure guides rapid linguistic predictions during naturalistic listening" by Jonathan R. Brennan and John T. Hale. These files include the stimulus (wav files), raw data (matlab format for the Fieldtrip toolbox), data processing paramters (matlab), and variables used to align the stimuli with the EEG data and for the statistical analyses reported in the paper.
- Keyword:
- linguistics, syntax, language, and eeg
- Citation to related publication:
- Brennan JR, Hale JT (2019) Hierarchical structure guides rapid linguistic predictions during naturalistic listening. PLoS ONE 14(1): e0207741. https://doi.org/10.1371/journal.pone.0207741
- Discipline:
- Social Sciences
-
- Creator:
- University of Michigan Museum of Paleontology and CTEES
- Description:
- Reconstructed CT slices for tooth in bone fragment of Colognathus obscurus (University of Michigan Museum of Paleontology catalog number UMMP 7506) as a series of TIFF images. Raw projections are not included in this dataset. The reconstructed slice data from the scan are offered here as a series of unsigned 16-bit integer TIFF images. The upper left corner of the first image (*_0000.tif) is the XYZ origin.
- Keyword:
- Paleontology, Fossil, CT, Reptile, UMMP, University of Michigan Museum of Paleontology, Triassic, and bf7ead64-3fff-a3f2-6b15-d04548dae2da
- Discipline:
- Science
-
- Creator:
- Lumeng, Julie C
- Description:
- Healthy full-term infants were enrolled in a longitudinal study designed to examine the development of infant eating behavior. Infant weight and length was measured, mothers completed questionnaires regarding infant eating behaviors, and infants were weighed and length measured at ages 1, 2, 4, 6 and 10 months. Trajectories of eating behaviors were identified using latent class growth modeling and bivariate analyses examined associations of infant eating behavior trajectory membership with infant and maternal characteristics. Cross-lagged analyses examined associations between BEBQ subscales and infant weight-for-length z-score.
- Keyword:
- infant, eating, weight gain, and feeding
- Citation to related publication:
- Harlan McCaffery, Julie Zaituna, Sophie Busch, Niko Kaciroti, Alison L. Miller, Julie C. Lumeng, Katherine L. Rosenblum, Ashley Gearhardt, Megan H. Pesch, Developmental trajectories of eating behaviors and cross-lagged associations with weight across infancy, Appetite, 2023, 106978
- Discipline:
- Health Sciences
-
- Creator:
- Rivera-Rivera, Luis Y., Moore, Timothy C., and Glotzer, Sharon C.
- Description:
- The dataset is organized as follows: the data for each of the three target structures is contained within a directory with the structure name (e.g., kagome, pyrocholore and snub-square). Within each structure directory, data obtained from alchemical and self-assembly simulations are separated into alchem and self-assembly directories respectively. An additional suboptimal-self-assembly directory is only present for the snub-square structure and contains the data for the pattern registration analysis discussed in the SI. For a detailed description of each file contained within each directory, please refer to the README file.
- Keyword:
- inverse design, self-assembly, triblock Janus particles, crystallization slot, and digital alchemy
- Citation to related publication:
- Rivera-Rivera, LY, Moore, TC & SC Glotzer. Inverse design of triblock Janus spheres for self-assembly of complex structures in the crystallization slot via digital alchemy. Soft Matter, 2023, 19, 2726-2736 doi: 10.1039/d2sm01593e
- Discipline:
- Engineering
-
- Creator:
- Chenevert, Thomas L., Malyarenko, Dariya, Amouzandeh, Ghoncheh, Pickup, Stephen, Zhou, Rong, Manning, Henry Charles, Gamon, Seth T., Shoghi, Kooresh I., Quirk, James D., Sriram, Renuka, Larson, Peder, Lewis, Mickael T., Pautler, Robia G., Kinahan, Paul E., and Muzi, Mark
- Description:
- Goals of this work quantify repeatability and reproducibility across multiple NIH/NCI Co-Clinical Imaging Research Resources Program (CIRP) preclinical MRI systems in performing diffusion measurement using a standardized acquisition protocol on a shared phantom containing temperature-controlled medium of known diffusivity. To achieve these goals, the CIRP Image Acquisition Data Processing (IADP) working group (WG) performed a round-robin study of an ice water-based DWI phantom using a detailed phantom preparation procedure and standardized DWI acquisition protocol, with both site- and core-lab generated ADC measurements derived from shared datasets.
- Keyword:
- diffusion MRI, pre-clinical MRI, apparent diffusion coefficient (ADC), repeatability, reproducibility, and accuracy
- Citation to related publication:
- Tomography 2023, 9, 375–386. https://doi.org/10.3390/tomography9010030
- Discipline:
- Health Sciences
-
- Creator:
- Umaña, Maria, Swenson, Nathan G, and Arellano, Gabriel
- Description:
- Identifying the functional traits that enable recovery after extreme events is necessary for assessing forest persistence and functioning, yet this is a difficult task because the traits mediating the responses to disturbance may vary depending on the disturbance type and over time. This study investigates the effects of traits on tree growth –for short and longer terms– in response to two vastly different extreme climatic events, droughts, and hurricanes, in a Puerto Rican forest.
- Keyword:
- Tropical tree, relative growth rates , and Puerto Rico
- Citation to related publication:
- Umaña, M. N. In review. The interplay of drought and hurricanes on tree recovery: insights from dynamic and weak functional responses. Forthcoming and Umana, M. (2023). Functional trait data across an elevational gradient of six tree species in El Yunque National Park, Puerto Rico in 2015 [Data set], University of Michigan - Deep Blue Data. https://doi.org/10.7302/7962-4t98
- Discipline:
- Science
-
- Creator:
- Ludlow, Andrew and Kim, Jeongjin
- Description:
- Part of the regulation of telomerase activity includes the alternative splicing (AS) of the catalytic subunit telomerase reverse transcriptase (TERT). Although a therapeutic window for telomerase/TERT inhibition exists between cancer cells and somatic cells, stem cells express TERT and rely on telomerase activity for physiological replacement of cells. Therefore, identifying differences in TERT regulation between stem cells and cancer cells is essential for developing telomerase inhibition-based cancer therapies that reduce damage to stem cells. In this study, we measured TERT splice variant expression and telomerase activity in induced pluripotent stem cells (iPSCs), neural progenitor cells (NPCs), and non-small cell lung cancer cells (NSCLC, Calu-6 cells). We observed that a NOVA1-PTBP1-PTBP2 axis regulates TERT alternative splicing (AS) in iPSCs and their differentiation into NPCs. We also found that splice-switching of TERT, which regulates telomerase activity, is induced by different cell densities in stem cells but not cancer cells. Lastly, we identified cell type-specific splicing factors that regulate TERT AS. Overall, our findings represent an important step forward in understanding the regulation of TERT AS in stem cells and cancer cells. These data and subsequent studies may reveal a splicing factor(s) or their binding site(s) that could be targeted with small molecule drugs or antisense oligonucleotides, respectively, to reduce telomerase activity in cancer cells and promote durable cancer remissions.
- Keyword:
- Telomere, telomerase, TERT, alternative RNA splicing
- Citation to related publication:
- Dynamics of TERT Regulation via Alternative Splicing in Stem Cells and Cancer Cells. Accepted in Plos One
- Discipline:
- Science
-
- Creator:
- Xu, Ying and Bradford, Nora
- Description:
- The data was collected from a survey study using Qualtrics described above. The data are in .csv format along with a codebook also in .csv format.
- Keyword:
- social chatbot, perception, and artificial intelligence
- Discipline:
- Social Sciences
-
- Creator:
- Ye, Zhengwei and Mi, Zetian
- Description:
- Generation of C2+ compounds using sunlight, carbon dioxide, and water provides a promising path for carbon neutrality. The exploration of a catalyst to break the bottleneck of C-C coupling, for constructing a rational artificial photosynthesis integrated device, is at the core. Herein, based on operando spectroscopy measurements, theoretical calculations, and feedstock experiments, it is discovered that gold, in conjunction with iridium, can catalyze the reduction of CO2, achieving C-C coupling by insertion of CO2 into -CH3. Owing to a combination of optoelectronic and catalytic properties, the assembly of AuIr with InGaN nanowires on silicon (AuIr@InGaN NWs/Si) enables the achievement of a C2H6 activity of 58.8 mmol‧g-1‧h-1 with a turnover number of 54,595 over 60 hours. A light-to-fuels efficiency of ~0.59% for solar fuels production from CO2 and H2O is achieved without any other energy inputs. This work provides a carbon-negative path for producing higher order C compounds.
- Keyword:
- Carbon dioxide reduction and Photocatalysis
- Discipline:
- Science
-
- Creator:
- Martin, Tara L, Young, LR, Goldsteen, D, Nunamaker, EA, Reynolds, P, Thompson-Iritani, S, Thurston, SE, and LaFollette, MR
- Description:
- This dataset contains the results of a survey of mouse handling methods by personnel working with laboratory mice. The survey included questions about preferred handling methods, barriers to use of refined handling methods, and a knowledge quiz about refined mouse handling. Data was collected via Qualtrics survey as described in the methodology section. This dataset is associated with the following publication, accepted by PLOS One: PONE-D-23-01633R1 Title: Using refined methods to pick up mice: A survey benchmarking prevalence & beliefs about tunnel and cup handling Authors: Lauren Young, Donna Goldsteen, Elizabeth A. Nunamaker, Mark J. Prescott, Penny Reynolds, Sally Thompson-Iritani, Sarah E. Thurston, Tara L. Martin, Megan R. LaFollette
- Keyword:
- Mouse, Refined Handling, Tunnel Handling, Cup Handling, Laboratory Animal, and Animal Care
- Citation to related publication:
- Young LR, Goldsteen D, Nunamaker EA, Prescott MJ, Reynolds P, Thompson-Iritani S, Thurston SE, Martin TL, LaFollette MR. Using refined methods to pick up mice: A survey benchmarking prevalence & beliefs about tunnel and cup handling. PLOS ONE. 2023. In Press.
- Discipline:
- Science
-
- Creator:
- Lumeng, Julie C
- Description:
- Healthy full-term infants were enrolled in a longitudinal study designed to examine the development of infant eating behavior. Infant weight and length was measured, mothers completed questionnaires regarding infant eating behaviors, and infant capacity for regulation of energy intake was evaluated by comparing intake between two days: one with feedings given on demand and one with feedings offered hourly. The infant's ability to downregulate intake in response to more frequent feedings was calculated.
- Keyword:
- infant, eating, weight gain, feeding, and energy regulation
- Citation to related publication:
- Reynolds, L. A., McCaffery, H., Appugliese, D., Kaciroti, N. A., Miller, A. L., Rosenblum, K. L., ... & Lumeng, J. C. (2023). Capacity for Regulation of Energy Intake in Infancy. JAMA pediatrics, 177(6), 590-598.
- Discipline:
- Health Sciences
-
- Creator:
- Lumeng, Julie C
- Description:
- Healthy full-term infants were enrolled in a longitudinal study designed to examine the development of infant eating behavior. Infant weight and length was measured, mothers completed questionnaires regarding infant eating behaviors, and infant sucking behavior was quantified using the NFANT device during a typical feeding. The predictive value of the NFANT-generated sucking metrics for infant weight gain was evaluated.
- Keyword:
- infant, eating, weight gain, and sucking
- Citation to related publication:
- Feldman, Keith, Katharine Asta, Ashley N. Gearhardt, Julie M. Sturza, Danielle Appugliese, Alison L. Miller, Katherine Rosenblum, Kai Ling Kong, Amanda K. Crandall, and Julie C. Lumeng. "Characterization of a Vigorous sucking style in early infancy and its predictive value for weight gain and eating behaviors at 12 months." Appetite (2023): 106525.
- Discipline:
- Health Sciences
-
- Creator:
- Raghani, Ravi M, Urie, Russell R, and Shea, Lonnie D
- Description:
- The IN were sampled during and after ICB and sequenced to identify gene expression signatures that correlated with sensitivity or resistance. We also analyzed gene expression at the IN prior to ICB treatment to identify markers predicting therapeutic response. Longitudinally interrogating an IN, to monitor changes associated with ICB response, presents a new opportunity to personalize care and investigate mechanisms underlying treatment resistance.
- Keyword:
- Immunotherapy resistance, Biomaterials, Metastasis, Checkpoint blockade, and Therapy monitoring
- Discipline:
- Engineering and Health Sciences
-
- Creator:
- Sant, Stacy-Lynn, Maleske, Christine, and Vanderboll, Kathryn
- Description:
- This dataset includes the full list of journals searched in this review and the complete literature search strategies. and No proprietary software is required to open any of these files.
- Keyword:
- Sport Management, Sport Events, Human Rights, and Scoping Review
- Discipline:
- Other
-
- Creator:
- Sant, Stacy-Lynn, Maleske, Christine, and Vanderboll, Kathryn
- Description:
- This dataset includes the list of journals searched in this review and the complete literature search strategies, as well as a full citation list and journal analysis of all studies included in the review. and No proprietary software is required to open any of these files.
- Keyword:
- Sport Management, Sport Events, Human Rights, and Scoping Review
- Discipline:
- Other
-
- Creator:
- Dewey, Ryan M, Livi, Stefano, Lepri, Susan T, Raines, Jim M, Ploof, Keeling, and The HIS Science Team
- Description:
- The data contained within the archive are for analysis and replication of Figure 2 in Livi et al. (2023), First Results from the Solar Orbiter Heavy Ion Sensor, Astronomy & Astrophysics. The readme.txt file contains more details on the contents of the archive and its files. Livi et al. (2023) reports the first solar wind composition measurements collected from the Heavy Ion Sensor (HIS) on the Solar Orbiter spacecraft. The period of study spans January-June 2022 during with the spacecraft completed nearly a full orbit about the Sun, from 0.3 AU to 1.0 AU. The solar wind composition within this publication are the first within the inner heliosphere. This paper describes the data and its processing from raw measurements (e.g., the data contained within this archive) to derived composition data products, and examines these composition data products about an interplanetary shock and interplanetary coronal mass ejection. Finally, these composition data are examined statistically and compared to historical data sets.
- Keyword:
- Solar Orbiter, Solar wind, Heavy ions, and Heavy Ion Sensor
- Citation to related publication:
- Livi, S., et al. (2023), First Results from the Solar Orbiter Heavy Ion Sensor, Astronomy & Astrophysics. https://doi.org/10.1051/0004-6361/202346304 and Owen, C., et al. (2020), The Solar Orbiter Solar Wind Analyser (SWA) suite, Astronomy & Astrophysics, 642. https://doi.org/10.1051/0004-6361/201937259
- Discipline:
- Science
-
- Creator:
- Thompson, Ellen P. and Ellis, Brian R.
- Description:
- Accurate prediction of physical alterations in carbonate reservoirs under dissolution is critical for development of subsurface energy technologies. The impact of mineral dissolution on flow characteristics depends on the connectivity and tortuosity of the pore network. Persistent homology is a tool from algebraic topology that describes the size and connectivity of topological features. When applied to 3D X-ray computed tomography (XCT) imagery of rock cores, it provides a novel metric of pore network heterogeneity. Prior works have demonstrated the efficacy of persistent homology in predicting flow properties in numerical simulations of flow through porous media. Its ability to combine size, spatial distribution, and connectivity information make it a promising tool for understanding reactive transport in complex pore networks, yet limited work has been done to apply persistence analysis to experimental studies on natural rocks. In this study, three limestone cores were imaged by XCT before and after acid-driven dissolution flow through experiments. Each XCT scan was analyzed using persistent homology. In all three rocks, permeability increase was driven by the growth of large, connected pore bodies. The two most homogenous samples saw an increased effect nearer to the flow inlet, suggesting emerging preferential flow paths as the reaction front progresses. The most heterogeneous sample showed an increase in along-core homogeneity during reaction. Variability of persistence showed moderate positive correlation with pore body size increase. Persistence heterogeneity analysis could be used to anticipate where greatest pore size evolution may occur in a reservoir targeted for subsurface development, improving confidence in project viability.
- Keyword:
- Carbonate dissolution, X-ray computed tomography, Porous media, Topology, and Persistent homology
- Citation to related publication:
- Thompson, E.P.; Ellis, B.R. (2023) Persistent Homology as a Heterogeneity Metric for Predicting Pore Size Change in Dissolving Carbonates. In Review.
- Discipline:
- Science and Engineering
-
- Creator:
- Pedde, Meredith
- Description:
- In this study, we took advantage of the randomized allocation of the US EPA's funding for school bus replacements and retrofits to causally assess the impacts of upgrading buses on student attendance through the EPA’s national School Bus Rebate Program. Specifically, we used classical intent-to-treat analyses for randomized controlled trials to compare the change in school district level attendance rates after vs before the 2012 through 2017 lotteries by funding selection status . We used overall district attendance rates since rates were not available for only school-bus riders.
- Keyword:
- School Bus Emissions, Diesel Air Pollution, and School Attendance
- Citation to related publication:
- Pedde, M., Szpiro, A., Hirth, R. et al. Randomized design evidence of the attendance benefits of the EPA School Bus Rebate Program. Nat Sustain (2023). https://doi.org/10.1038/s41893-023-01088-7
- Discipline:
- Health Sciences