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- Creator:
- Mirshams Shahshahani, Payam
- Description:
- Investigating minimum human reaction times is often confounded by the motivation, training, and state of arousal of the subjects. We used the reaction times of athletes competing in the shorter sprint events in the Athletics competitions in recent Olympics (2004-2016) to determine minimum human reaction times because there's little question as to their motivation, training, or state of arousal. The reaction times of sprinters however are only available on the IAAF web page for each individual heat, in each event, at each Olympic. Therefore we compiled all these data into two separate excel sheets which can be used for further analyses.
- Keyword:
- minimum reaction time, sprinter, Olympics, Athletics, sex difference, starting block, and false start
- Citation to related publication:
- Mirshams Shahshahani P, Lipps DB, Galecki AT, Ashton-Miller JA (2018) On the apparent decrease in Olympic sprinter reaction times. PLoS ONE 13(6): e0198633. https://doi.org/10.1371/journal.pone.0198633
- Discipline:
- Engineering, Health Sciences, Science, Other, and General Information Sources
-
- Creator:
- MacEachern, Mark and Muzyk, Andrew
- Description:
- The systematic review explores the role of the emergency department in naloxone distribution and harm reduction strategies associated with opioid use.
- Keyword:
- Opioid use, Systematic review, Emergency department, Literature searches, and Naloxone
- Citation to related publication:
- Gunn AH, Smothers ZPW, Schramm-Sapyta N, Freiermuth CE, MacEachern M, Muzyk AJ. (2018). The emergency department as an opportunity for naloxone distribution. Western Journal of Emergency Medicine, 19(6), 1036-42. doi: 10.5811/westjem.2018.8.38829 https://doi.org/10.5811/westjem.2018.8.38829
- Discipline:
- Health Sciences
-
- Creator:
- Gliske, Stephen V and Stacey, William C
- Description:
- This data is part of a large program to translate detection and interpretation of HFOs into clinical use. A zip file is included which contains hfo detections, metadata, and Matlab scripts. The matlab scripts analyze this input data and produce figures as in the referenced paper (note: the blind source separation method is stochastic, and so the figures may not be exactly the same). A file "README.txt" provides more detail about each individual file within the zip file.
- Keyword:
- hfo, high frequency oscillation, ripple, fast ripple, blind source separation, non-negative matrix factorization, and temporal variability
- Discipline:
- Science, Engineering, and Health Sciences
-
- Creator:
- Moyer, Cheryl A
- Description:
- Data reflect the knowledge, attitudes, and beliefs of health care providers regarding neonatal near-misses in Neonatal Intensive Care Units (NICUs) in southern Ghana.
- Keyword:
- qualitative methods, neonatal mortality, neonatal near-misses, and developing country
- Discipline:
- Health Sciences
-
- Creator:
- Berlin, Nicholas and MacEachern, Mark
- Description:
- This systematic review and meta-analysis assesses decision aids in the context of patients considering post-mastectomy breast reconstruction. and NOTE: An updated Read Me file was added to this data set on May 24, 2018 replacing the original.
- Keyword:
- Post-mastectomy, Decision-making, Systematic review, Decision aids, Meta-analysis, and Breast reconstruction
- Citation to related publication:
- Berlin NL, Tandon VJ, Hawley ST, et al. Feasibility and Efficacy of Decision Aids to Improve Decision Making for Postmastectomy Breast Reconstruction: A Systematic Review and Meta-analysis. Med Decis Making. 2019;39(1):5–20. https://doi.org/10.1177/0272989X18803879
- Discipline:
- Health Sciences
-
- Creator:
- Veinot,Tiffany,C., Michigan Department of Health & Human Services, U.S. Census Bureau, American Community Survey, Data Driven Detroit, Okullo, Dolorence, and Michigan Department of Vital Statistics
- Description:
- Health status data includes data about the health of persons within a census tract in Metropolitan Detroit, measured at the census tract level. This includes data about 1) mortality by condition; 2) exposures to toxic substances; and 3) disability. Coverage for all data: 10-county Detroit-Warren-Ann Arbor Combined Statistical Area.
- Keyword:
- Community Health, Mortality Rates by Condition , Disability, Elevated Blood Lead Levels, Census Tract level, All-Cause Mortality Rates, and Spatial Measures
- Discipline:
- Health Sciences and Social Sciences
-
- Creator:
- Detroit Residential Parcel Survey, United States Postal Service, Wayne County Register of Deeds, US Census, Yu, Deehan, Public and Affordable Housing Research Corporation (PAHRC), Veinot, Tiffany, RealtyTRAC, National Low Income Housing Coalition (NLIHC), Okullo, Dolorence, Wayne County Treasurer, Health Resource and Services Administration (HRSA), and Data Driven Detroit
- Description:
- This dataset includes census tract-level data concerning housing in Metropolitan Detroit. The data includes: 1) Total housing units and total mortgages in the tract; 2) Land use; 3) Real estate information (foreclosures, sales transactions, and home values); 4) Vacant housing; 5) Housing age and available facilities; 6) Housing condition; and 7) Spatial measures of subsidized housing in the tract. Data coverage should say 2006 to 2015.
- Keyword:
- Housing Conditions, Community Health, Subsidized Housing Locations, Availability of Kitchen and Plumbing Facilities, Vacant Properties, Census tract level, Age of Housing, Spatial Measures, Home Sale Transactions, Land Use by Category, Housing Units and Ownership, Housing Values, and Foreclosed Properties
- Discipline:
- Social Sciences and Health Sciences
-
- Creator:
- MacEachern, Mark P
- Description:
- The dataset represents the complete, reproducible search strategies for all literature databases searched during the systematic review. The Endnote file and the Endnote import files contain all citations considered for inclusion in the review.
- Keyword:
- addiction, nursing, systematic review, education, and substance use
- Citation to related publication:
- Smothers, Zachary MBS; Reynolds, Victoria PharmD; McEachern, Mark MLIS; Derouin, Anne L. DNP, RN, CPNP, FAANP; Carter, Brigit M. PhD, RN, CCRN; Muzyk, Andrew PharmD Substance Use Education in Schools of Nursing, Nurse Educator: May/June 2018 - Volume 43 - Issue 3 - p 136-139. https://doi.org/10.1097/NNE.0000000000000449 and https://www.ncbi.nlm.nih.gov/pubmed/28858952
- Discipline:
- Health Sciences
-
- Creator:
- MacEachern, Mark P MLIS, Bennett, Katelyn G MD, Preminger, Aviva MD, Berlin, Nicolas MD, and Vercler, Christian J MD
- Description:
- The dataset includes the reproducible search strategies for all literature databases searched during the review, the key articles used to generate relevant search terms and test the effectiveness of the searches, the Endnote library that has all citations considered for inclusion, a flow chart describing the screening process, and the screening forms used for inclusion and exclusion.
- Keyword:
- Plastic surgery, Professionalism, Surgery, and Social media
- Citation to related publication:
- Bennett K, Berlin N, MacEachern MP, Buchman S, Vercler C. (2018). The ethical and professional use of social media in surgery - A systematic review of the literature. Plastic and Reconstructive Surgery, 142(3), 388e-398e. PMID: 30148789. https://doi.org/10.1097/prs.0000000000004692
- Discipline:
- Health Sciences
-
- Creator:
- Saini, Sameer D
- Description:
- See attached survey and codebook
- Discipline:
- Health Sciences
-
- Creator:
- MacEachern, Mark P
- Description:
- The dataset represents the complete search strategies for all literature databases searched during the systematic review. The Endnote library that contains all citations is also included.
- Keyword:
- Systematic review, Anti-osteoporotic drugs, Fractures, Surgery, and Meta-analysis
- Discipline:
- Health Sciences
-
- Creator:
- MacEachern, Mark P
- Description:
- The dataset represents the complete search strategies for all literature databases searched during the systematic review. The Endnote and Excel files of all citations considered for inclusion in the review are also included.
- Keyword:
- systematic review, pharmacy, education, addiction, and substance abuse
- Discipline:
- Health Sciences
-
- Creator:
- Kerber, Kevin A and Meurer, William J
- Description:
- Data set
- Keyword:
- dizziness
- Discipline:
- Health Sciences
-
- Creator:
- Piette, John and Abbott, Patricia A
- Description:
- Contained within is a subset of the larger dataset collected in La Paz, Bolivia in 2014. This data contains the analytic dataset (cross-sectional/descriptive) that includs the PACIC, Morisky, PHQ8, AUDIT, and a subset of socidemographic characteristics for NCD patients in La Paz.
- Keyword:
- Global Health, Bolivia, and Non-communicable disease
- Discipline:
- Health Sciences
-
- Creator:
- Okullo, Dolorence, Gomez-Lopez, Iris N., Goodspeed, Robert, Reddy, Shruthi, Veinot, Tiffany C, Clarke, Phillipa J., and Data Driven Detroit
- Description:
- The information and education environment refers to: 1) the presence of information infrastructures such as broadband Internet access and public libraries in a location; 2) a person’s proximity to information infrastructures and sources; 3) the distribution of information infrastructures, sources and in a specific location; and 4) exposure to specific messages (information content) within a specific location. Coverage for all data: 10-county Detroit-Warren-Ann Arbor Combined Statistical Area.
- Keyword:
- Residential Broadband Data Adoption Rates, Census tract level, Broadband Internet Access and Speed, Colleges and Universities, Public Libraries, Spatial Measures, and Schools
- Discipline:
- Science, Social Sciences, and Health Sciences
-
- Creator:
- Yoshida, Sei and Swanson, Joel A
- Description:
- The rapid activation of the mechanistic target of rapamycin complex-1 (mTORC1) by growth factors is increased by extracellular amino acids through yet-undefined mechanisms of amino acid transfer into endolysosomes. Because the endocytic process of macropinocytosis concentrates extracellular solutes into endolysosomes and is increased in cells stimulated by growth factors or tumor-promoting phorbol esters, we analyzed its role in amino acid–dependent activation of mTORC1. Here, we show that growth factor-dependent activation of mTORC1 by amino acids, but not glucose, requires macropinocytosis. In murine bone marrow–derived macrophages and murine embryonic fibroblasts stimulated with their cognate growth factors or with phorbol myristate acetate, activation of mTORC1 required an Akt-independent vesicular pathway of amino acid delivery into endolysosomes, mediated by the actin cytoskeleton. Macropinocytosis delivered small, fluorescent fluid-phase solutes into endolysosomes sufficiently fast to explain growth factor–mediated signaling by amino acids. Therefore, the amino acid–laden macropinosome is an essential and discrete unit of growth factor receptor signaling to mTORC1
- Keyword:
- growth factor signaling, Macropinosomes, and mTORC1
- Discipline:
- Health Sciences
-
- Creator:
- Okullo, Dolorence, Yan, Xiang (Jacob), Data Driven Detroit, Veinot, Tiffany C., Gomez-Lopez, Iris N., and Goodspeed, Robert
- Description:
- The food environment is: 1) The physical presence of food that affects a person’s diet; 2) A person’s proximity to food store locations; 3) The distribution of food stores, food service, and any physical entity by which food may be obtained; or 4) A connected system that allows access to food. (Source: https://www.cdc.gov/healthyplaces/healthtopics/healthyfood/general.htm) Data included here concern: 1) Food access; and 2) Liquor access. Spatial Coverage for most data: 10-county Detroit-Warren-Ann Arbor Combined Statistical Area, Michigan, USA. See exception for grocery store data below.
- Keyword:
- Food Deserts, Census tract level, Full-Line Grocery Stores, Modified Retail Food Environment Index (MRFEI), Farmer’s Markets, Spatial Measures, and Fast Food Establishments
- Discipline:
- Social Sciences, Health Sciences, and Other
-
- Creator:
- Meurer, William
- Description:
- Full analytical dataset with labels in SPSS
- Keyword:
- Diagnostic testing
- Discipline:
- Health Sciences
-
- Creator:
- Shtull-Leber, Eytan
- Description:
- We present the SAS code used to conduct the data manipulation and analysis for our research on pre-hospital midazolam use before and after RAMPART.
- Keyword:
- emergency medical services, knowledge translation, status epilepticus, benzodiazepines, midazolam, EMS, and Seizure
- Discipline:
- Health Sciences
-
- Creator:
- Reference USA, City of Detroit, ESRI, Data Driven Detroit, and Veinot, Tiffany C.
- Description:
- Active living resources include spaces and organizations that facilitate physical activity, including 1) park land, 2) recreation areas (including parks, golf courses, amusement parks, beaches and other recreational landmarks); and 3) recreation centers (including gyms, dancing instruction, martial arts instruction, bowling centers, yoga instruction, sports clubs, fitness programs, golf course, pilates instruction, personal trainers, swimming pools, skating rinks, etc.) Coverage for all data: 10-county Detroit-Warren-Ann Arbor Combined Statistical Area.
- Keyword:
- Recreation Areas, Park Land, Census tract level, Metropolitan Detroit, Spatial Measures, Recreation Centers, and Michigan
- Discipline:
- Health Sciences, Social Sciences, and Other
-
- Creator:
- Data-Driven Detroit, Goodspeed, Robert, Reference U.S.A., Veinot, Tiffany C., Yan, Xiang, State of Michigan Department of Elections, and Okullo, Dolorence
- Description:
- The Social Environment refers to characteristics of the people and institutions in a census tract, including: 1) Religious organizations (churches and places of worship); and 2) Voter turnout for the 2012 Presidential Election. Coverage for all data: 10-county Detroit-Warren-Ann Arbor Combined Statistical Area.
- Keyword:
- Voter Turnout, Religious Institutions, Spatial Measures, and Census Tract Level
- Discipline:
- Health Sciences and Social Sciences
-
- Creator:
- Meurer, William
- Description:
- Dataset for analysis in SPSS
- Discipline:
- Health Sciences
-
- Creator:
- Carson, William F. IV
- Description:
- Data files pertaining to the manuscript entitled: "THE STAT4/MLL1 EPIGENETIC AXIS REGULATES THE ANTIMICROBIAL FUNCTIONS OF MURINE MACROPHAGES"
- Discipline:
- Health Sciences
-
- Creator:
- Meurer, William J., Meka, Arjun, and Porath, Jon
- Description:
- Introduction: Diagnostic testing is common in the emergency department. The value of some testing is questionable. The purpose of this study was to assess how varying levels of benefit, risk, and costs influenced an individual’s desire to have diagnostic testing. Methods: A survey through Amazon Mechanical Turk presented hypothetical clinical situations: low risk chest pain and minor traumatic brain injury. Each scenario included three given variables (benefit, risk, and cost), that was independently randomly varied over four possible values (0.1%, 1%, 5%, 10% for benefit and risk and $0, $100, $500, and $1000 for the individual’s personal cost for receiving the test). Benefit was defined as the probability of finding the target disease (traumatic intracranial hemorrhage or acute coronary syndrome). Results: A total of 1000 unique respondents completed the survey. Increasing benefit from 0.1% to 10%, the percent of respondents who accepted a diagnostic test went from 28.4% to 53.1%. [OR: 3.42 (2.57-4.54)] As risk increased from 0.1% to 10%, this number decreased from 52.5% to 28.5%. [OR: 0.33 (0.25-0.44)] Increasing cost from $0 to $1000 had the greatest change of those accepting the test from 61.1% to 21.4%, respectively. [OR: 0.15 (0.11-0.2)] Conclusions: The desire for testing was strongly sensitive to the benefits, risks and costs. Many participants wanted a test when there was no added cost, regardless of benefit or risk levels, but far fewer elected to receive the test as cost increased incrementally. This suggests that out of pocket costs may deter patients from undergoing diagnostic testing with low potential benefit.
- Discipline:
- Health Sciences
-
- Creator:
- Grosh, Karl and Li, Yizeng
- Description:
- In a sensitive cochlea, the basilar membrane response to transient excitation of any kind--normal acoustic or artificial intracochlear excitation--consists of not only a primary impulse but also a coda of delayed secondary responses with varying amplitudes but similar spectral content around the characteristic frequency of the measurement location. The coda, sometimes referred to as echoes or ringing, has been described as a form of local, short term memory which may influence the ability of the auditory system to detect gaps in an acoustic stimulus such as speech. Depending on the individual cochlea, the temporal gap between the primary impulse and the following coda ranges from once to thrice the group delay of the primary impulse (the group delay of the primary impulse is on the order of a few hundred microseconds). The coda is physiologically vulnerable, disappearing when the cochlea is compromised even slightly. The multicomponent sensitive response is not yet completely understood. We use a physiologically-based, mathematical model to investigate (i) the generation of the primary impulse response and the dependence of the group delay on the various stimulation methods, (ii) the effect of spatial perturbations in the properties of mechanically sensitive ion channels on the generation and separation of delayed secondary responses. The model suggests that the presence of the secondary responses depends on the wavenumber content of a perturbation and the activity level of the cochlea. In addition, the model shows that the varying temporal gaps between adjacent coda seen in experiments depend on the individual profiles of perturbations. Implications for non-invasive cochlear diagnosis are also discussed.
- Discipline:
- Engineering and Health Sciences
-
- Creator:
- MacEachern, Mark
- Description:
- This collection contains literature searches for published evidence syntheses in the health sciences.
- Keyword:
- health sciences, evidence syntheses, systematic reviews, scoping reviews, and literature searches
- Discipline:
- Health Sciences
20Works -
- Creator:
- MacEachern, Mark P and Criss, Cory N
- Description:
- While collaboration with industry is paramount to innovation, the recent emphasis on industrial relationship transparency has sparked new guidelines, research studies, and standardizations focused on re-defining conflict of interest. There is limited data on defining the specific financial amount wherein a conflict of interest is relevant. This study is the first to assess the potential financial effects on high-quality clinical data, or the “indirect sponsorship”.
- Keyword:
- Sponsorship, Indirect sponsorship, Surgery, Robotic surgery, and DaVinci
- Citation to related publication:
- Criss CN, MacEachern MP, Matusko N, Dimick JB, Maggard-Gibbons M, Gadepalli SK. The Impact of Corporate Payments on Robotic Surgery Research: A Systematic Review. Ann Surg. 2019 Mar; 269 (3): 389-396. doi: 10.1097/SLA.0000000000003000. PMID: 30067545. https://doi.org/10.1097/SLA.0000000000003000
- Discipline:
- Health Sciences
-
- Creator:
- MacEachern, Mark
- Description:
- The search data supports a literature review project on lifestyle therapies for the management of atrial fibrillation. The data included in the dataset are the reproducible search strategies (in docx) and the exported results of all citations from all databases (txt and ris files). These searches and exported result files contain all citations originating from the database searches that were considered for inclusion.
- Keyword:
- literature searches, atrial fibrillation, lifestyle therapy, and lifestyle therapies
- Citation to related publication:
- Abdul-Aziz AA, Altawil M, Lyon A, MacEachern M, Richardson CR, Rubenfire M, Pelosi F Jr, Jackson EA. Lifestyle Therapy for the Management of Atrial Fibrillation. Am J Cardiol. 2018 May 1;121(9):1112-1117. doi: 10.1016/j.amjcard.2018.01.023. PubMed PMID: 29650239., https://www.ncbi.nlm.nih.gov/pubmed/29650239, and https://doi.org/10.1016/j.amjcard.2018.01.023
- Discipline:
- Health Sciences
-
- Creator:
- Liu, Y , Ettinger, AS, Téllez-Rojo, M, Sánchez, BN, Zhang, ZZ, Cantoral, A, and Hu, H
- Description:
- We used data collected from participants of the Early Life Exposures in Mexico to ENvironmental Toxicants (ELEMENT) study, which consists of three sequentially-enrolled birth cohorts of pregnant women. Research protocols of this study were approved by the Institutional Review Board at University of Michigan and the Mexico National Institute of Public Health. We obtained informed consent from mothers and informed assent from children prior to enrollment.
- Citation to related publication:
- Liu, Y., Ettinger, A. S., Téllez-Rojo, M., Sánchez, B. N., Zhang, Z., Cantoral, A., Hu, H., & Peterson, K. E. (2020). Prenatal Lead Exposure, Type 2 Diabetes, and Cardiometabolic Risk Factors in Mexican Children at Age 10–18 Years. The Journal of Clinical Endocrinology & Metabolism, 105(1), 210–218. https://doi.org/10.1210/clinem/dgz038
- Discipline:
- Health Sciences
-
- Creator:
- Hatch, Nan E.
- Description:
- Crouzon FGFR2-C342Y/+ and wild type littermate pups on a BALB/c congenic background were injected with lentivirus expressing TNAP enzyme or phosphate buffered saline shortly after birth. Mice were euthanized 4 weeks after birth for analyses.
- Keyword:
- craniofacial, bone, craniosynostosis, FGFR2, TNAP, mouse model, and development
- Discipline:
- Health Sciences
-
- Creator:
- Kue, Jessie and Meurer, William
- Description:
- NHAMCS is an annual survey of emergency department visits. and SAS programs are required to read this data.
- Keyword:
- emergency department and hypertension
- Citation to related publication:
- Kue, J., & Meurer, W. (2020). Association between blood pressure, race, ethnicity and likelihood of admission to the hospital from United States emergency departments – A cross sectional study. F1000Research, 9, 1116. https://doi.org/10.12688/f1000research.24757.1
- Discipline:
- Health Sciences
-
- Creator:
- Wen, Ai, Foxman. Betsy, Srinivasan, Usha , Goldberg, Deborah , Marrs, Carl F , Owen, John, Wing, Deborah A., Misra, Dawn , Cronenwett, Anna , Ponnaluri, Sreelatha, Miles-Jay, Arianna, Bucholz, Brigette, and Abbas, Khadija
- Description:
- This is the bacterial DNA data extracted from the gram stain slides. The targeted bacteria genera and species include: Atopobium spp., bacterial vaginosis-associated bacterium (BVAB) types 1, 2 and 3 in the order Clostridiales, Escherichia coli, Gardnerella vaginalis, Group B Streptococcus, Lactobacillus spp., Mobiluncus spp., Mycoplasma spp., and Ureaplasma spp. We also used a primer set for Lactic Acid Bacteria (LAB) that includes lactic acid producing bacteria of the genera Lactobacillus, Pediococcus, Leuconostoc, and Weissella. We calculated the relative proportion of each bacterial taxon using the bacterial copies measured by each specific bacteria primer divided by the total bacterial copies. The limit of detection was 100 copies and readings lower than the limit were considered negative
- Citation to related publication:
- Wen A, Srinivasan U, Goldberg D, Owen J, Marrs CF, Misra D, Wing DA, Ponnaluri S, Miles-Jay A, Bucholz B, Abbas K, Foxman B. Selected vaginal bacteria and risk of preterm birth: an ecological perspective. J Infect Dis. 2014 Apr 1;209(7):1087-94. https://doi.org/10.1093/infdis/jit632. Epub 2013 Nov 22. PMID: 24273044; PMCID: PMC3952673. and Foxman B, Wen A, Srinivasan U, Goldberg D, Marrs CF, Owen J, Wing DA, Misra D. Mycoplasma, bacterial vaginosis-associated bacteria BVAB3, race, and risk of preterm birth in a high-risk cohort. Am J Obstet Gynecol. 2014 Mar;210(3):226.e1-7. https://doi.org/10.1016/j.ajog.2013.10.003. Epub 2013 Oct 4. PMID: 24096128; PMCID: PMC3943817.
- Discipline:
- Health Sciences
-
- Creator:
- Figueroa, Carlos A., Computational Vascular Biomechanics Lab, University of Michigan, and et al.
- Description:
- This collection concerns the CRIMSON (CardiovasculaR Integrated Modelling and SimulatiON) software environment. CRIMSON provides a powerful, customizable and user-friendly system for performing three-dimensional and reduced-order computational haemodynamics studies via a pipeline which involves: 1) segmenting vascular structures from medical images; 2) constructing analytic arterial and venous geometric models; 3) performing finite element mesh generation; 4) designing, and 5) applying boundary conditions; 6) running incompressible Navier-Stokes simulations of blood flow with fluid-structure interaction capabilities; and 7) post-processing and visualizing the results, including velocity, pressure and wall shear stress fields. , The minimum specifications to run CRIMSON are: Any AMD64 CPU (note: Intel Core i series are AMD64), Windows (only tested on Windows 10 but might work on Windows 7), 8 GB of RAM , If you are running non-trivial models you will want to have: Quad core CPU or higher, Solid state drive for storing data, Windows, 16 GB of RAM, Dedicated discrete GPU for rendering models. , and Software in this collection is a snapshot; please visit https://github.com/carthurs/CRIMSONGUI & www.crimson.software for more general information and the most up to date version of the software.
- Keyword:
- Blood Flow Simulation, Patient-specific, Open-source Software, Image-based simulation, Cardiovascular Medical Image, Segmentation, and Finite Element Simulation
- Citation to related publication:
- CRIMSON: An Open-Source Software Framework for Cardiovascular Integrated Modelling and Simulation C.J. Arthurs, R. Khlebnikov, A. Melville, et al. bioRxiv 2020.10.14.339960; doi: https://doi.org/10.1101/2020.10.14.339960
- Discipline:
- Health Sciences and Engineering
4Works -
Lu-177 DOTATATE Anonymized Patient Datasets
User Collection- Creator:
- Dewaraja, Yuni K and Van, Benjamin J
- Description:
- This collection is comprised of a number of works that collectively represent the imaging studies and information necessary for dosimetric analysis of a patient treated with Lutathera. All works may be used as standalone datasets or in conjunction with the others in this collection depending on the analysis performed. Files are stored using the DICOM standard widely accepted for storage and transmission of medical images and related information. All patient private information has been anonymized using MIM commercial software (MIM Software Inc.). Data from 2 patients, referred to as patient 4 and patient 6, has been provided in this collection and is divided among 6 works as outlined below:, 1) Pre-Therapy Diagnostic Images. Description: Patient diagnostic scans performed prior to Lutathera treatment. Used for identifying lesions and measuring progression. Note that the date of the baseline scan may be several months before the Lutathera treatment and changes in the anatomy are possible. Files: (1) Ga68 Dotatate PET/CT, Either: (1) MRI, (1) standalone diagnostic CT, 2) Planar Whole Body Scans. Description: Planar whole body Lu-177 scans taken at 4 time points within a week after treatment. Two views (Anterior and Posterior) and 3 energy windows (one main window at 208 keV and 2 adjacent scatter windows) are available for each time point. The units of this image is counts. Energy window information, acquisition data/time and duration can be found in DICOM header. Files: (6) individual images at each time point (24 total images per patient) , 3) SPECT/CT Scans. Description: Lu-177 SPECT/CT scans at 4 time points within a week after treatment (same time points as the planar scans). Images were acquired on a Siemens Intevo system and reconstructed using xSPECT Quant. The units of this image is Bq/mL. Information on the reconstruction, acquisition date/time, duration, Lu-177 administration time and activity can be found in the DICOM header. Files: (1) Folder with reconstructed SPECT slices per time point (4 folders total per patient), (1) Folder containing co-registered CT slices per time point (4 folders total per patient), 4) Lesion and Organ Volumes of Interest. Description: DICOM RT structure files containing organ and lesion volumes of interest (VOI) that were defined on the CT of the scan1 SPECT/CT in 3). Organs were defined using semi-automatic tools (atlas based and CNN-based) while lesions were defined manually by a radiologist guided by baseline scans. Only lesions >2 cc were defined. Files: (1) File containing organ contours, (1) File containing lesion contours, 5) Time Integrated Activity Maps. Description: A DICOM file containing the time-integrated activity map over all 4 time points within a week after treatment. This combines the SPECT/CT scans provided in 3) into a single integrated activity map. This map was generated via the MIM MRT Dosimetry package: The 4 time points were registered to the reference SPECT scan (time point 1) using a contour intensity based SPECT alignment and the voxel-level time-activity data was fit using exponential functions. Voxel-level integration was performed to generate the TIA map. The units of this image is Bq/mL * sec. Files: (1) Folder with Time-integrated activity image per patient, and 6) Projection Data and CT based Attenuation Coefficient Maps. Description: SPECT projection data for each of the 4 Lutathera scans taken within a week after treatment is provided in 3 forms: unaltered, Siemens [Reformatted], and Siemens [Advanced]. The difference between the Projections and the [Advanced] Projections is that the [Advanced] consists of uncorrected raw projection data and the other the corrected projection data (e.g. camera uniformity corrections). The [Advanced] projections are used in xSPECT reconstruction (where all corrections are done during the reconstruction), while the other is used in Flash 3D reconstruction. CT-based attenuation coefficient maps (mumaps) are provided for each of the 4 scans taken within a week after treatment. Two methods are provided for each mumap: xSPECT and F3D as the matrix size is different for the 2 cases (256 x 256 for xSPECT and 128 x 128 for Flash3D). Files: (3) Folders containing raw SPECT projections, (2) Folders containing CT attenuation coefficient maps (mumaps)
- Keyword:
- Lu-177, Lutathera, Dosimetry, Radionuclide, and CTMRIPET
- Discipline:
- Health Sciences
6Works -
- Creator:
- Lim, Hongki and Dewaraja, Yuni K.
- Description:
- Internally administered targeted radionuclide therapy (TRT) with radio-labelled targeting molecules that deliver cytotoxic radiation to tumor has been used successfully to treat multiple cancers. Lu-177, used increasingly in TRT, emits both beta particles that deliver the therapeutic effect. FDA recently approved a fixed activity (4 cycles of 7.4 GBq/cycle as in NETTER -1) administered every 8 weeks. With the patient studies under this treatment, we collected CT images and corresponding volume of interest (organs, lesions) contours.
- Keyword:
- Lu-177, CT, Segmentation, Organ, Tumor, Label
- Discipline:
- Health Sciences
-
- Creator:
- Meurer, William
- Description:
- SPSS is required to access processed dataset in .sav format. Model output is provided as a word document, and Qualtrics survey instrument is included as PDF and .docx, where .docx version contains survey logic and question numbers.
- Keyword:
- Diagnostic Testing, Emergency Medicine, and Financial Incentives
- Citation to related publication:
- Iyengar, R., Winkels, J., Smith, C. M., Meka, A. P., MD, Porath, J. D., MD, & Meurer, W. J., MD, MS. (2019, January 21). The Effect of Financial Incentives on Patient Decisions to Undergo Low-Value Head CT Scans. https://doi.org/10.31219/osf.io/4mdfw
- Discipline:
- Health Sciences
-
- Creator:
- Crisp, Dakota N., Saggio, Maria L., Scott, Jared, Stacey, William C., Nakatani, Mitsuyoshi, Gliske, Stephen V., and Lin, Jack
- Description:
- This data and scripts are meant to test and show seizure differentiation based on bifurcation theory. A zip file is included which contains real and simulated seizure waveforms, Matlab scripts, and metadata. The matlab scripts allow for visual review validation and objective feature analysis. The file “README.txt” provides more detail about each individual file within the zip file. and Data citation: Crisp, D.N., Saggio, M.L., Scott, J., Stacey, W.C., Nakatani, M., Gliske, S.F., Lin, J. (2019). Epidynamics: Navigating the map of seizure dynamics - Code & Data [Data set]. University of Michigan Deep Blue Data Repository. https://doi.org/10.7302/ejhy-5h41
- Keyword:
- Bifurcation, Epilepsy, Seizure, and Divergence
- Citation to related publication:
- Saggio, M.L., Crisp, D., Scott, J., Karoly, P.J., Kuhlmann, L., Nakatani, M., Murai, T., Dümpelmann, M., Schulze-Bonhage, A., Ikeda, A., Cook, M., Gliske, S.V., Lin, J., Bernard, C., Jirsa, V., Stacey, W., 2020. In pre-print. Epidynamics characterize and navigate the map of seizure dynamics. bioRxiv 2020.02.08.940072. https://doi.org/10.1101/2020.02.08.940072
- Discipline:
- Engineering, Science, and Health Sciences
-
- Creator:
- Almazroa, Ahmed
- Description:
- The dataset includes 3 different files: 1) MESSIDOR dataset file contains 460 original images and 460 images for every single ophthalmologist manual marking in total of 3220 images for the entire file. 2) Bin Rushed Ophthalmic center file and contains 195 original images and 195 images for every single ophthalmologist manual marking in total of 1365 images for the entire file. 3) Magrabi Eye center file and contains 95 original images and 95 images for every single ophthalmologist manual marking in total of 665 images for the entire file. The total of all the dataset images are 750 original images and 4500 manual marked images. The images are saved in JPG and TIFF format., NOTE ON THE DATA: Depositor accidentally left out 50 images from the BinRushed folder from the original deposit. A corrected BinRushed folder that includes these 50 images was added to this data set on May 21, 2018., and NOTE ON DOWNLOADING: The file "MESSIDOR.zip" is too large to be downloaded through Deep Blue Data. Please use Globus to download this file.
- Keyword:
- Medical imaging, Optic cup, Image processing, Optic disc, Glaucoma, Optic nerve head, Image segmentation, Fundus images, and Automated glaucoma screening system
- Citation to related publication:
- Ahmed Almazroa, Sami Alodhayb, Essameldin Osman, Eslam Ramadan, Mohammed Hummadi, Mohammed Dlaim, Muhannad Alkatee, Kaamran Raahemifar, Vasudevan Lakshminarayanan, "Retinal fundus images for glaucoma analysis: the RIGA dataset", Proc. SPIE 10579, Medical Imaging 2018: Imaging Informatics for Healthcare, Research, and Applications, 105790B (6 March 2018); doi: 10.1117/12.2293584; https://doi.org/10.1117/12.2293584
- Discipline:
- Health Sciences